Current Issue

September  2020

  • Volume 57
  • Issue 9
  • Page Nos. 86

Guest Editorial

Need for Regulatory Affairs Personnel Development

PAGE 5-6

Dr. Anantha Narayana, is the Chief Scientific Officer, AYURVIDYE TRUST, Bangalore. He Championed the Notifications of Supplements and Nutraceuticals Regulations, FSSAI, 2016 Updated in 2017 and Phytopharmaceuticals as Drugs under Drugs & Cosmetics Act & rules, 2016. He is a recipient of I...

Dr D B Anantha Narayana

Bengaluru

Review Article

INTRUSION OF GLYCOGEN SYNTHASE KINASE-3β TO COPE VARIOUS CARDIAC DISORDERS AT MOLECULAR LEVEL

PAGE 7-18

All eukaryotes consist of kinases with a serine/threonine residue called glycogen synthase kinase 3 (GSK-3) which mediates cellular functions by causing phosphorylation of glycogen synthase and regulating glucose metabolism. It establishes disease mechanisms through cell signalling and different ...

Vishwakarma Vishal Kumara , Ansari Tarique Mahmoodb*, Maiti Anupa , Srivastav Ritesh Kumarc, Bagga Paramdeepb and Ahsan Faroghb

Original Research Articles

SYNTHESIS, BIOLOGICAL EVALUATION AND DOCKING STUDIES OF NON HEPATOTOXIC 5-SUBSTITUTED THIAZOLIDINE-2, 4-DIONES AS ANTIDIABETIC, ANTI-HYPERLIPIDEMIC, ANTI-OXIDANT AND CYTOTOXIC AGENTS

PAGE 19-37

A series of eleven thiazolidine-2, 4-dione (TZD) derivatives, were synthesized and characterized by FT-IR, 1 H NMR and mass spectral analysis. All the synthesized TZD derivatives were screened for their in vitro and in vivo anti-diabetic and antioxidant, activities and cytotoxicity. In vivo antih...

Shukla Karuna S.a,b, Pandey Shailendrac , Chawla A Poojad*

SYNTHESIS, CHARACTERIZATION AND SKELETAL MUSCLE RELAXANT ACTIVITY FOR NOVEL [1,4]DIAZEPINO[2,3-G]QUINOXALINE DERIVATIVES

PAGE 38-44

Novel [1,4]diazepino[2,3-g]quinoxaline derivatives 5a-5i were designed, synthesized and characterized by spectroscopic method and elemental analysis. The title compounds were screened for skeletal muscle relaxant. Among the synthesized analogs, compound 5g and compound 5h revealed significant ske...

D. Visagaperumala*, Pemmadi Raghuveer Varmab, R. Jayakumarc , Vineeth Chandyd

Evaluation of Antibacterial Potential of Extracts of Mocharas (gum of Bombax malabaricum) against certain bacterial strains

PAGE 45-52

Mocharas is the gum of the tree Bombax malabaricum DC which belongs to the family Bombaceae. In Unani system of medicine, it is used in the treatment of various infectious diseases. In the present study, various extracts of Mocharas (B. malabaricum) were tested for their antibacterial activity ag...

Akhtar Sadaa*, Rauf Abdura , Rehman Sumbula and Siddiqui Mohd Zakira

DEVELOPMENT AND VALIDATION OF NEW STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF ELBASVIR AND GRAZOPREVIR IN BULK AND PHARMACEUTICAL DOSAGE FORM

PAGE 53-59

The present study describes the development and validation of a new stability indicating RP-HPLC method for simultaneous estimation of elbasvir and grazoprevir in bulk and pharmaceutical dosage form. The chromatographic separation was done by using reverse phase YMC column (4.6 x 250mm, 5μm).The...

Dandu Girijaa* and Basu Venkateswara Reddyb

FORMULATION, DEVELOPMENT AND EVALUATION OF HERBAL TRANSDERMAL PATCH FOR FRACTURE HEALING

PAGE 60-66

Peristrophe bicalyculata posses expectorant, analgesic, anti-inflamatory, antipyretic and antibacterial properties and has been traditionally used for the management of pain, sprain, and bone fracture. In this study we have tried to incorporate bioactive components of P. bicalyculata in transderm...

Kumar Aadesha*, Rana Mahendraa,b, Bisht Madanc and Rana Amitaa

Evaluation of Hepatoprotective Effects of Selected Fruit Peel Extracts and Their Poly Herbal Mixture on CCl4 Induced Hepatotoxicity: An in vivo Study

PAGE 67-74

The main aim of this study was to screen the selected fruit peel extracts and their polyherbal mixture (PHM) for hepatoprotective activity. Male wistar albino rats (180-200 g), divided into 12 groups after induction of hepatotoxicity, were treated with selected fruit peel extracts and PHM and at ...

Kondepudi Gana Manjushaa*, Battu Ganga Raob and P Balakrishnaiaha

Short Notes

SIMULTANEOUS ESTIMATION OF ASPIRIN AND OMEPRAZOLE IN LABORATORY SAMPLE BY DIFFERENT UV SPECTROPHOTOMETRIC TECHNIQUES

PAGE 75-81

The aim of the present work was to develop simple, precise and economic UV- spectrophotometric methods for the simultaneous estimation of aspirin and omeprazole in a laboratory sample. The absorbance maxima (λmax) for detection of aspirin and omeprazole were selected as 274 nm and 302 nm, respec...

Wani Rakesh Ma , Kashid Arun Mb*, Amita Ghatgea , Sumita Sahoob

Recent Issue
Quick Contact