Current Issue

August  2017

  • Volume 54
  • Issue 08
  • Page Nos. 92

Review Article

LYMPHATIC DELIVERY: CONCEPT, CHALLENGES AND APPLICATIONS

PAGE 5-22
The lymphatic system is an additional circulatory system throughout the entire body. It plays a critical role in the recognition of immune system and response to disease. Lymphatic delivery has attracted a lot of attention for providing preferential chemotherapy and enhancing bioavailability of dr...
Bora C. R., Prabhu R. H. and Patravale V. B.*

Original Research Articles

Synthesis of some new pyrimidine heterocycle bearing nucleus as potent Anticancer AGENTS

PAGE 23-28
A series of pyrimidine derivatives were synthesized by the reaction of substituted aromatic aldehyde with substituted acetophenones in alkaline medium to form chalcones (1). further treatment of these derivatives with thiourea in alkaline medium afforded 4,6-disubstituted pyrimidine-2-thiones (2a1...
Chaurasiya H. S.*, Sharma G. K. and Pathak D.

Steroidal constituents and a fatty acid ester from the fruit peels of Citrus sinensis (L.) Osbeck

PAGE 29-34
Citrus sinensis (L.) Osbeck (Rutaceae), is distributed in tropical and temperate regions of India, China, Mexico, Congo and East Africa. Its fruit peel is carminative, stomachic, tonic and is used to cure acne, earache, anorexia, colds, coughs and toothache. The essential oil is antiseptic, anti-i...
khan Md. A., Abuzer A. and Mohammed A.*

Studies on urea co-inclusion complexes of ebastine for steep improvement in dissolution profile

PAGE 35-45
Urea co-inclusion technique has been successfully utilized for steep enhancement in dissolution rate of ebastine (EB), a BCS class II potent drug. EB is a novel second generation H1 receptor antagonist used for prevention of chronic idiopathic urticaria and allergic rhinitis. It exhibits low aqueo...
Dhall M. and Madan A. K.*

Formulation and characterization of ritonavir loaded proniosomes for oral drug delivery

PAGE 46-53
Proniosomes of ritonavir were prepared by slurry method using Span 60, maltodextrin and cholesterol. The ratio of concentration of Span 60 to cholesterol was altered while keeping concentration of drug and maltodextrin constant. Prepared formulations were studied for micromeritic properties, entr...
Sande T. A.*, Sayyad F. J., Patil A. V. and Mohite D. D.

A NOVEL STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE DETERMINATION OF VALSARTAN AND HYDROCHLOROTHIAZIDE IN BULK AND PHARMACEUTICAL FORMULATIONS

PAGE 54-61
The prime aim of the present investigation was to develop and validate a novel, precise, accurate, specific, rapid and economical stability- indicating isocratic reverse phase liquid chromatography method for the quantitative simultaneous estimation of valsartan and hydrochlorothiazide in bulk and...
B. Venkateswara Rao,*, S. Vidyadhara, and M. V. Basaveswara Rao

DEVELOPMENT AND VALIDATION OF LC-MS/MS METHOD FOR THE SIMULTANEOUS DETERMINATION OF PIOGLITAZONE AND VOGLIBOSE IN HUMAN PLASMA

PAGE 62-73
A reliable, simple, robust and sensitive LC-MS/MS (Liquid Chromatography tandem Mass Spectrometric) method has been developed and validated that employs protein precipitation extraction method for the simultaneous determination of Pioglitazone and Voglibose in human plasma by using miglitol as in...
Hemavathi G.* and Hipparagi S. M.

Anti-hyperglycemic activity of Citrus limon leaves in Streptozotocin induced diabetic rats

PAGE 74-80
Citrus limon leaves is a traditional herbal medicine which is used as a munching dietary supplement for the management of diabetes in parts of Kerala. However there is no evidence supporting the claim. The objective of the present study was to evaluate the anti-diabetic effect of Citrus limon leav...
Thomas L.* and Kamath J. V.

Short Notes

A smart approach for formulation process of escitalopram loaded bio-nano suspension for brain delivery via novelistic EAM (External acoustic meatus) platform

PAGE 81-84
Our aim was to target antidepressant drug loaded nano-suspension using novel bioexcepient isolated from kernels of Prunus amygdalus and explore the capability of external acoustic meatus as novel acoustic drug delivery system. We isolated the biomaterial and performed various physicochemical eval...
Raina D.*, N. V. Satheesh Madhav
Recent Issue
Quick Contact