Current Issue

October  2018

  • Volume 55
  • Issue 10
  • Page Nos. 84

Guest Editorial

INDIAN PHARMA INDUSTRY – WHAT’S NEXT?

PAGE 5-6

Dr. Shenoy completed his Bachelor’s, Master’s and Ph.D studies in Pharmaceutical Sciences from College of Pharmaceutical Sciences (COPS), Manipal. Prior to joining Novartis, he has worked for Lupin Limited, Mylan Laboratories Ltd., Cadila Pharmaceuticals Ltd., Novavax (USA), Northeastern Univ...

Dr Dinesh Shenoy, Ph.D.
Head-Pharmaceutical Development, India
Head-TRD-GV Site,
Global Drug Development /Technical Research & Development
Novartis Healthcare Pvt. Ltd

Review Article

A SCIENTIFIC REVIEW ON PHYTO-PHARMACOLOGICAL PROPERTIES OF Tribulus terrestris LINN.

PAGE 7-15

Tribulus terrestris Linn. (Zygophyllaceae) has been used since ancient times to treat various health ailments. Different parts of the plant have been used by traditional physicians, however the dried entire fruit is more commonly used as ‘Gokshura’ and ‘Ikshugandha’ in Ayurveda and as ‘...

Waseem M.a, Rauf A.b and Rehman S.b

Original Research Articles

Synthesis and Anti-diabetic Activity of Some Aryloxypropanolamine Derivatives

PAGE 16-23

Aryloxypropanolamine plays an important role in several biological activities. It shows multiple actions such as β-blocking, anxiolytic, antihypertensive and inhibition of cytochrome p450. A series of ten aryloxypropanolamine derivatives 6a–6j were synthesized and evaluated for anti-diabetic a...

Puranik H. H.a, Jadhav S. B.a*, Bandawane D. D.b and Bhalekar P. A.a

Use of Factorial Design in Optimization of Microwave Assisted Organic Synthesis of some Azoles

PAGE 24-33

In the era of environment friendly chemistry, Microwave Assisted Organic Synthesis (MAOS) has proved to be an effective tool to achieve maximum yield in minimum time without compromising on quality. The present work focuses on synthesis of some bioactive heterocyclic azoles using MAOS. However, t...

Somani R. R.a*, Sanap G. J.a and Chaskar P. K.a

Estimation of Metformin hydrochloride and Teneligliptin in pharmaceutical formulation by high performance thin layer chromatography

PAGE 34-39

A new, accurate and precise high performance thin layer chromatographic (HPTLC) method has been developed for simultaneous analysis of metformin hydrochloride and teneligliptin in tablet formulation. The chromatographic separations were achieved on TLC plates precoated with silica gel G60 F2...

Patel V. B.a*, Patel J. S.a and Shah D. A.a

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR ESTIMATION OF SATRANIDAZOLE FROM ITS FORMULATION

PAGE 40-48

A sensitive stability-indicating high performance liquid chromatography (HPLC) method was developed and validated for quantitative estimation of satranidazole (SAT), a new nitroimidazole with potent antiamoebic activity and accessible in market as tablet and dry syrup either alone or in combinati...

Shirode A. R.a*, Dhumal A. P.a and Kadam V. J.a

AN INVESTIGATION ON ANTIDIABETIC AND ANTIOXIDANT ACTIVITY OF EXTRACT OF LEAVES OF AMARANTHUS POLYGAMUS IN STREPTOZOTOCIN INDUCED DIABETIC RATS

PAGE 49-55

The aim of the present study was to assess the antihyperglycemic and antioxidant activites of the methanol extracts of Amaranthus polygamus (MEAP). Indian folklore suggests the plant as good liver tonic and is recommended as vegetable for diabetic and anemic patients. MEAP was evaluated ...

Singh M. P.a*, Shukla S. T.b and Pateriya A.b

Short Notes

HPLC Determination of N-Methylethanolamine in Diphenhydramine Hydrochloride Drug Substance by Pre-column Derivatization

PAGE 56-62

N-Methylethanolamine is the side chain of the drug diphenhydramine hydrochloride. A sensitive high performance liquid chromatography method with pre-column derivatization was developed and validated for the determination of N-methylethanolamine impurity in diphenhydramine hydroc...

Anerao A.a*, Dighe V.a, Gupta A.a, Patil C.a and Pradhan N. a

IR QUANTIFICATION OF MODAFINIL IN BULK AND ORAL DOSAGE FORM

PAGE 63-65

Simple and sensitive infrared spectrophotometric method has been developed for the estimation of modafinil in tablet dosage form and the Beer’s Law concentration range was found to be 1.0mg to 2.5mg. The correlation coefficient for the method was found to be 0.999 and the developed method was a...

Sekar A. M.a*, Anbazhagan S.a, Agalya R.a, Asha T.a, Nivetha K.a and Barathi M.a

Analytical Method Development and its Validation for Evaluation of Polyherbal Formulation

PAGE 66-68

Talekt capsule is a branded polyherbal formulation used for enhancing the immune response to dermal infections and also for treating skin disorders. Curcumin and embelin, which are the active constituents of Haridra and Vidanga, respectively were used as marker compounds for developing a simple, ...

Karthik S.a and Jadhav A. P.a*

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