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Ever since the Dietary Supplement Health and Education Act (DSHEA) was notified in the US in 1994, discussion on botanicals for wellness continues. Botanicals to be used for providing wellness health benefits opened up a large market for consumer benefits. Nations like India ...
The key objective of the present review was to collect the latest literature on technological advancements towards microballoons as novelistic buoyant drug delivery systems. Microballoons are hollow microspheres with a potential approach for gastric retention, offering controlled release of the ...
Metformin is an oral antihyperglycemic medication used to treat type 2 diabetes. BCS-III classification of medications includes metformin hydrochloride, which has a high solubility and a low permeability. This study’s objective was to develop wet granulated metformin hydrochloride tablets using...
A Fluorescence-Linked Immunosorbent Assay (FLISA) targeting β-cross-sheet α-synuclein protein, a crucial marker in Parkinson’s Disease (PD), was assessed using in vitro assay with a rotenone-induced PD cellular model. The study aimed to evaluate FLISA’s applicability with the inhouse develo...
In this research paper, we report an eco-friendly diffuse reflectance infrared fourier transform spectroscopic (DRIFTS) method for quantifying neratinib. The systematic method development was performed as per the recent analytical quality by design concept. The critical method variables such as r...
The purpose of the current research was to prepare a delayed-release system of mini-tablets (gastroprokinetic drug). The model drug (itopride hydrochloride) was formulated with the combination of methylcellulose (free-flowing agent) and Eudragit® S-100 (enteric coating agent) for delayed release...
Probiotics are beneficial microbes that have a beneficial effect on humans as well as animals. Despite their advantages, probiotics face viability challenges during storage and while passing through the upper gastrointestinal tract. This study was designed to develop an encapsulated system of Sac...
Combining dapagliflozin and saxagliptin presents a promising strategy for managing type 2 diabetes mellitus by leveraging their distinct, yet complementary, mechanisms of action. A novel bilayer tablet with a 5 mg sustained release layer of saxagliptin and a 10 mg immediate release layer of dapag...
The present investigation is concerned with the formulation and development of rivaroxaban (RN) effervescent granules using a dry granulation process. A 23 factorial design was employed using Design-Expert® software to develop an ideal formulation. Formulations were evaluated, and showed outstan...