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It is indeed heartening to note that the Indian Government has notified Rules for fast-track launch of new, breakthrough drugs including block-buster molecules, waiving or bypassing clinical trials in India under Chapter V of the Rules, where the relevant drug has already bee...

Cognitive decline with aging is a concern, particularly in neurodegenerative and mental diseases. Cognitive enhancers focus on cholinergic and monoaminergic systems, but Phosphodiesterases (PDEs) have gained interest in enhancing cognition by increasing intracellular accessibility of additional m...

Our study focuses on screening ligands against the target 6Y2E using the iGemDock docking program, encompassing phytochemical, synthetic and marine sources, suggesting suitability for oral use against SARS-CoV-2 Main protease. Docking process involves iGemDock program for assessment, Argus Labs, ...

Embelin, isolated from Embelia ribes berries is a major constituent isolated by the Soxhlet process and possesses antimicrobial activity. In this report, we develop and evaluate the topical antimicrobial embelin niosomal cream formulation. Niosomal formulation of embelin was formulated using a th...

Diabetic Foot Ulcers (DFUs) are open ulcers or sores on the foot with a bony prominence. They are a frequent manifestation of uncontrolled diabetes mellitus and often increase the risk of infection. DFUs typically take longer to heal, sometimes resulting in severe complications such as amputation...

The objective of this investigation was to formulate an ideal nanostructured lipid carrier (NLC) for glibenclamide in oral capsules. Employing factorial design, the NLC formulation was achieved through high-pressure homogenization using Design-Expert® software, optimized using a 32 -factor exper...

It is alarming and concerning that, as time progresses, due to lifestyle modifications and the emergence of resistant microbial strains, the need to explore novel drugs against them is escalating and becoming a trend. Natural products are versatile substances with remarkable qualities that could ...

Hemodialysis patients often face challenges related to adherence to medications and psychological well-being, including depression. Understanding the prevalence of depression and adherence patterns among these patients is crucial for optimizing their care and improving outcomes. This study aimed ...

Pharmacological studies have shown that Carica papaya possessed anti-inflammatory, antioxidant and wound healing properties. The present study was outlined to extract, formulate and evaluate C. papaya transdermal patches. Transdermal patches were made by solvent casting method utilizing HPMC as r...

Stable emulsions represent an effective formulation approach for masking the bitter taste of many drugs. Due to some unwanted side effects observed recently, synthetic surfactants are facing disfavor during the formulation of emulsions. The present study was undertaken to assess the potential of ...