Articles Accepted

Derivitisation of Pregabalin for simultaneous estimation with methylcobalamine using Ultra Violet Spectroscopy
by Dr. SAMPADA D DALVI, 28 May 2019

Accurate, sensitive, and economical procedures for simultaneous estimation of Pregabalin and Methylcobalamine in tablet dosage form have been developed. The method employed is simultaneous equation method. This method employs the formatiom and solving of simultaneous equation using 528 nm and 568 nm as the two wavelengths for forming equation. Drugs obey Beer’s law in the concentration range 10-50 μg/ml for Pregabalin and 10-50 μg/ml for Methylcobalamine. The proposed spectrophotometric method was validated and successfully applied for the assay of both drug combinations in several laboratory prepared mixtures and commercial tablets.

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November 2020
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