Articles Accepted

FORMULATION AND EVALUATION OF MEDICATED CANDY OF TENOFOVIR ALAFENAMIDE FUMARATE FOR THE TREATMENT OF HUMAN IMMUNODEFICIENCY SYNDROME
by Ms. Priya Mourya, 25 Mar 2020

Medicated candies are solid oral dosage form containing medicaments in flavored and sweetened base. The main advantages associated with buccal drug delivery are systemic absorption of drug and also increased bioavailability and avoidance of hepatic first pass metabolism. Tenofovir alafenamide fumarate is a choice of drug for the treatment of human immunodeficiency virus due to its potency and fewer side effects over tenofovir disoproxil fumarate. The aim of the present research work is to formulate and evaluate candy of tenofovir alafenamide fumarate for pediatric and geriatric patients for better patient acceptability. Medicated candy of tenofovir alafenamide fumarate were prepared by using heating and congealing method, and the prepared formulation were evaluated on various parameters such as organoleptic properties, weight variation, friability, hardness, drug content, and in vitro drug dissolution time profile. On the basis of above studies it can be concluded that medicated candy can be utilized as alternative option for oral drug delivery for pediatric and geriatric patients.

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November 2020
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