Articles Accepted

SYNTHESIS 1,3-THIAZOLE DERIVATIVES AS A REVIEW
by Dr. REBAZ ANWAR OMER, 01 Apr 2020

Many heterocyclic compounds are containing nitrogen atom used in drug development. Thiazole is one of the most important heterocyclic compounds in drug design, which was containing sulfur and nitrogen atom. Different site reaction in thiazole compounds extends to new drug synthesis and important role in medicinal chemistry. Thiazole and derivatives were found in widely biological activities such as anti-inflammatory, anti-diabetic, anti-microbial, anti-cancer, anti-convulsant, anti-HIV, anti-hypertensive, anti-Alzheimer, anti-oxidant and anthelmintic. The aim of this review is the corroborating procedure which was available for synthesis 1,3-thiazole derivatives.

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