Articles Accepted

Antifungal Topical Gel of Leaves Extract of Amaranthus viridis L. for Treatment of Cutaneous Candidiasis
by Dr. Ashlesha Pandit, 30 Jul 2019

The objective of the study was to prepare antifungal gel using leaves of Amaranthus viridis for the treatment of skin candidiasis. The leaves were studied for pharmacognostic evaluation. The powder of leaves was tested for phytoconstituents. The plant extract was evaluated for the Minimum inhibitory concentration (MIC), Minimum bactericidal concentration (MBC) and antifungal activity. Gel was prepared and evaluated for pH, viscosity, homogeneity and grittiness. The MIC and MBC of extract was found to be 600 mg. The zone of inhibition of extract was obtained at 21.2±0.2mm, which confirmed antifungal activity, due to presence of phenolic compound. Gel exhibited good antifungal activity, good spreadability, extrudability and high viscosity. Thus, gel loaded with leaves extract of Amaranthus viridis is a good choice for the treatment of cutaneous candidiasis.

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October 2019
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