Articles Accepted

Lipid as an Excipient for Design and Development of Formulations
by Ms. Apoorva Vinod More, 11 Nov 2019

Lipids are present abundantly in human body in several forms. Different types of lipids are available with diverse physical properties, based on which suitable lipids can be selected for development of formulation. Lipids are also available for specific purpose like lubrication, emulsification, emollient and enhancement of bioavailability. Conventionally many lipids were used in formulation of tablets, capsules, emulsions and cosmetics. In recent years use of lipids for drug delivery has been extended to Solid Lipid Nanoparticle (SLN), Nanostructured Lipid Carriers (NLC), Self-Micro Emulsifying Drug delivery System (SEDDS), etc which are the emerging technologies designed to address challenges like solubility and bioavailability of poorly water soluble drugs. This paper mainly focuses on different types of formulation in which lipids are used and parameters which are critical for selection of lipid in any dosage form development. Several examples are quoted for different uses of lipids, finally challenges in use of lipids and regulatory aspects are discussed.

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