Articles Accepted

A Review on Microsphere: Types, Methods and Evaluation
by Dr. darsh gautam, 27 Jun 2023

Controlled drug delivery system (CDDS) allows active pharmaceutical agent (API) to be released over extended periods of time, ranging from days to months by using drug-encapsulating devices. Such systems have a number of merits over conventional drug delivery techniques, including the ability to customize drug release rates, safeguard delicate medications, and improve patient comfort and compliance. Due to their capacity to encapsulate a variety of drugs, biocompatibility, high bioavailability, and sustained drug release properties, polymeric microspheres are excellent vehicles for many controlled delivery applications. This review's research is geared toward enhancing large-scale production, preserving drug stability, and managing better drug release rates. In this paper, fabrication techniques for microparticles and the key variables affecting drug release rates from encapsulated particles are discussed. Based on recent literature, this review provides data of microsphere’s production techniques for use in biomedical applications. The various types of microspheres such as on the basis of drug release pattern (matrix, coated, reservoir) and on the basis of drug delivery system (mucoadhesive, floating, bio-adhesive, radioactive, polymeric, and magnetic, etc) is also discussed. The preparation and characterization processes used to prepare these microspheres are also covered in this review.

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