Table of Contents

July  2013

  • Volume 50
  • Issue 7
  • Page Nos. 1-64

Review Article

Amorphous Pharmaceutical Solids: A Review

Amorphous pharmaceutical solids have recently attracted the interest of pharmaceutical scientistsbecause of a continuous increase in the number of developmental drug molecules that are insoluble.Amorphous state of the drug provides several pharmacokinetic advantages over the crystalline state.In thi...
Dhokchawle B. V., Tauro S. J., and Bhandari A. B.

Original Research Articles

Forced Degradation Study of Eletriptan by Using Ultra High Performance LiquidChromatography (UHPLC)

A simple, fast, precise and accurate ultra high performance liquid chromatography method wasdeveloped for degradation study of eletriptan hydrobromide (EH) under exaggerated conditions.An Inertsil ODS C18 (250 x 4.6 mm, 5?m) column in isocratic mode was used with mobile phasecomprising of water, met...
Sahu S., Singh R.M, Mathur S.C., Sharma D. K., Saini P.K., Duggal D.,Tyagi V. and Singh G. N.

Comparative Assessment of Topical Formulations by PerformingTransmembrane Diffusion and Permeation Using Diffusion Cells

Skin penetration of a drug and the effect of formulation additives can be evaluated by performingdiffusion studies. In the present study semisolid cream formulation comprising of bacteriostatic antibioticof 2 different creams have been compared for the penetration of drug. Based on these in vitro re...
Sawarkar S., Gursalkar T., and Deshpande S.

Pharmacognostical, Phytochemical and Anti-Microbial Activity ofAn Ayurvedic Formulation Nishakatakadi Kashayam

The objective of the present study was to develop quality parameters to evaluate and standardize the polyherbal formulation and also to study the eight crude drugs viz. Curcuma longa - rhizome (Manjal),Salacia oblonga- root bark (Ekanayakam), Emblica officinalis- pericarp (Nellika), Strychnos potato...
Radha A., Prabhakaran M., Paul M., Sreevalsan A., Sebastian J.,Verghese J., and Jolly C.I.

Design and in Vitro Evaluation of Mucoadhesive Buccal Films ofLercanidipine Hcl

Lercanidipine hydrochloride, an anti hypertension drug, undergoes extensive first pass metabolism toinactive metabolites leading to very poor oral bioavailability. To overcome this problem, buccal films ofLercanidipine hydrochloride were prepared by solvent casting method, employing HPMC, HPC (alone...
Doddayya H., Patil S.S., Suman M., Kumar P., and Udupi R.H.

Short Notes

Evaluation of Mangrove Plants as Putative HIV-Protease Inhibitors

Ethanol (Direct) extracts of mangrove plants, namely, Avicennia officinalis Linn. and Rhizophoramucronata Lam. were included for the present in vitro study. Pepsin was used as a substitute for HIVproteaseto evaluate inhibitory activity of these extracts, as pepsin has close resemblance with HIVprote...
Rege A. A., and Chowdhary A. S

Evaluation of Market Samples of Mayur Puccha BhasmaUsing Namburi Phased Spot Test (NPST)

Mayur Puccha Bhasma(calx of peacock feather), an unique animal product used traditionally in themanagement of Chardhi(vomiting), Hikka(hiccough), Swasa(respiratory disorder) was preparedaccording to the prescription in the Ayurvedic classics and subjected to various bhasma pariksha (testsfor calx),i...
Kotrannavar V.S., Sarashetty R.S. and Tambhekar N.
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