Table of Contents

September  2013

  • Volume 50
  • Issue 9
  • Page Nos. 1-64

Review Article

A Review on use of Lithium in Bipolar Disorder

PAGE 5
Bipolar disorder (previously called manic depressive illness) is a medical condition involving changes in the brain function leading to dramatic mood swings. It is characterized by the occurrence of at least one manic or mixed-manic episode, commonly treated with mood stabilizers. Sometimes, antip...
Bhavsar D. B., Desai U. S., Phatak A. A., and Chaudhari P. D.

Original Research Articles

EXTRACTION, ISOLATION, CHARACTERIZATION, SEMISYNTHESIS AND BIOLOGICAL EVALUATION OF BERBERINE FROM ROOTS OF BERBERIS ARISTATA

PAGE 18
A methanolic extract of roots of Berberis aristata was prepared by using hot percolation method. Berberine was isolated from the above extract and characterized by IR, 1HNMR, mass spectrometry and elemental analysis. A series of 8-(substituted acetophenone) berberine derivatives was synthesized by...
Mittal J., Chaudhary K., Kumar N. and Pathak D.*

Development of Novel In-Situ Liquid Bandages of Diclofenac Sodium

PAGE 25
The present work was aimed at developing dermatologically acceptable film forming composition containing an anti-inflammatory agent. The prepared liquid bandages were found to be opaque, compatible, possessing high drug content with sufficient viscosity and thickness. Pores were observed on the s...
Harish T., Deveswaran R., Bharath S., Basavaraj B.V. and Madhavan V.

A Validated Uv Spectroscopic Method for the Simultaneous Determination of Benzil Impurity in Phenytoin Sodium

PAGE 30
A simple, accurate, precise, economical and reproducible UV spectrophotometric method has been developed and validated for the simultaneous determination of benzil impurity in phenytoin in synthetic mixture without their prior separation. The method employs formation and solving of simultaneous e...
Korde P. and Pai P.N.S.

Evaluation of anti-diarrhoeal activity of Punica granatum stem Bark

PAGE 34
Evaluation of anti-diarrhoeal effect of Punica granatum stem bark ethanolic extract was carried out on various experimental animal models of diarrhea. Different paragons used were castor oil induced diarrhoea, magnesium sulphate induced diarrhoea, castor oil induced enteropooling and gastrointesti...
Khan N., Hugar S., Patil V., Nanjappaiah H.M., Gaviraj E.N., and Kalyane N.V

Thermoreversible, Mucoadhesive In Situ Gelling Formulations for Nasal Delivery of Propranolol Hydrochloride

PAGE 41
Mucoadhesive, thermoreversible propranolol hydrochloride formulations were made to overcome firstpass metabolism, to prolong the drug residence time in the nasal cavity and to improve the therapeutic efficacy. In situ gelling formulations were prepared by cold technique using Pluronic F-127, Pluro...
Bhat R., Abbas Z. and Swamy N.G.N.

Short Notes

Isolation and Characterization of Aristolochic Acid - I From Aristolochia Indica Linn. Leaves

PAGE 52
Aristolochic Acids (AAs) are major components of plants in Aristolochia species. The plant Aristolochia indica Linn. has diverse biological actions such as analgesic, anti-diabetics, anti-bacterial, anti-fungal and treatment of malaria and fevers. Here, we report a new and simple isolation method ...
Mulik M.B. and Laddha K.S.
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