Table of Contents

April  2014

  • Volume 51
  • Issue 4
  • Page Nos. 1-68

Review Article

PEGylation: concept and applications in Cancer therapeutics

PAGE 5-19
Polyethylene glycol-ylation (PEGylation) is a phenomenon of modification of a protein, peptide, or non-peptide molecule by linking of one or more polyethylene glycol chains. These synthetic polymers have received FDA approval for internal use. It is an effective method of delivering therapeutic pr...
Khan T. A.* and Gohel A. K.

Original Research Articles

Development of HPTLC method for simultaneous estimation of Ofloxacin and Ornidazole in combined dosage form

PAGE 20-25
A simple and accurate high performance thin layer chromatographic (HPLTC) method have been developed and validated as per ICH guidelines for estimation of Ofloxacin (OFL) and Ornidazole (ORN) in combined dosage form. The mobile phase was acetone : water : toluene : triethylamine (5.8:1.5:2:1.6 V/...
Dighade N. R.*, Shende M. D. and Kasture A. V.

Cytomorphological and Phytochemical analysis of Abrus precatorius Linn

PAGE 26-35
Abrus precatorius belongs to the family Fabaceae and is a slender woody perennial climber. The genus Abrus is native to India, introduced to warmer regions of the world. It has gained scientific importance as a potential herbal remedy in treatment of chronic nephritis, diabetes, cancer, bacterial ...
Reddy S. K., Sandhya S*, Vinod K.R, Asia B. and Banji D.

FORMULATION AND EVALUATION OF TRANSDERMAL DRUG DELIVERY SYSTEM OF ATENOLOL USING CHITOSAN

PAGE 36-41
The effect of various concentrations of chitosan as a polymer was investigated for the transdermal delivery of atenolol across human cadaver skin by using dimethylsulfoxide as a penetration enhancer. Atenolol-chitosan matrix type patches were formulated using different polymer concentrations. Aten...
Kamble M. D.*, Dhokchawle B. V. and Tauro S. J.

Comparative Assessment of Chlorpheniramine Maleate Permeation through Cellulose Acetate Membrane and Sheep Nasal Mucosa

PAGE 42-49
The present research work was aimed to develop nasal mucoadhesive microspheres of chlorpheniramine maleate (CPM) & to compare its permeation rate through sheep nasal mucosa and cellulose acetate membrane. The impact of different concentrations of polymer and the dispersion media were evaluated fo...
Mouzam M. I. * and Dehghan MHG

SIMULTANEOUS ESTIMATION OF AMLODIPINE BESYLATE AND INDAPAMIDE BY DUAL WAVELENGTH SPECTROPHOTOMETRIC METHOD FOR COMBINED PHARMACEUTICAL DOSAGE FORM

PAGE 50-54
A simple, accurate, precise, rapid, economical UV spectrophotometry method, dual wavelength spectrophotometry, has been developed and validated for estimation of Indapamide (IND) and Amlodipine besylate (AML) in combined tablet dosage form and can be used in routine analysis. In this method, the ...
Patel M. P.*, Patel M. R., Hasumati R., Noolvi M. N and Shah N.

Short Notes

DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF DEFLAZACORT

PAGE 55-68
UV spectrophotometric method has been developed for the estimation of deflazacort in pure and its pharmaceutical formulations. In UV method deflazacort showed absorption maximum at 242.8nm in methanol medium and it obeys Beers law in the concentration range of 5-25µg/mL....
Deepti K and Rai A
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