Table of Contents

January  2019

  • Volume 56
  • Issue 01
  • Page Nos. 100

Guest Editorial

2019 – Time for Innovations through Collaborations

PAGE 5-6

At very outset, I wish all our readers and pharmaceutical scientists a very Happy New Year. 2019 is dawning on the Indian research community in general and all pharmaceutical research professionals in particular. The Prime Minister has come up with “JAI VIGYAN” and “JAI ANUSANDHAN” in sup...

Dr. Gopakumar G. Nair
Editor,
Indian Drugs

Review Article

Review on ethnomedicinal uses, phytochemical constituents and pharmacological evidence on leaf extract of Persea americana and Vernonia amygdalina of the African continent - A Review

PAGE 7-24

People on the African continent frequently consume Persea americana and Vernonia amygdalina for food and medicinal purposes. The review is an effort to compile ethnomedicinal, phytochemical and pharmacological knowledge is the above two plants from the year 2000 till now. A search was ca...

Boadu A.a*, Singh S.a, Karpoormath R.a and Nlooto M.a

Original Research Articles

SYNTHESIS AND EVALUATION OF NAPROXEN ESTER PRODRUGS

PAGE 25-31

The present works deals with simple and efficient method of improving therapeutic efficacy of naproxen by retarding gastrointestinal side effects through masking of carboxylic group chemically. This is achieved by synthesis of ester prodrugs of naproxen with various naturally available antioxidan...

Dhokchawle B. V.a,*, Asirvatham S.a, Tauro S. J.a, Bhandari B. A.b, Babu S. S.a and Shetty R. R.a

Search for novel anti-fertility agent by monitoring in vitro metabolic inhibition, cell motility and cellular interactions of nifedipine analogues

PAGE 32-39

Current family planning measures predominantly target a female clientele, with relatively few significant developments in male fertility regulation. At present, only effective methods for contraception in men are those that prevent sperm transport, such as condoms and vasectomy. Thus, in an attem...

Bagle S.a, Malbari K.a, Joshi M.b and Kanyalkar M.a*

ANTI-ANAEMIC POTENTIAL OF BUTANOLIC EXTRACT OF PIPER BETEL LEAVES AND TRITICUM AESTIVUM GRASS IN RATS: AN IN VIVO APPROACH

PAGE 40-44

Several plants have been used for medicinal purposes since long. Piper betel and Triticum aestivum are traditionally used as herbal medicines. The objective of this study was to estimate the antianaemic potential of butanolic extract of Piper betel leaves and Tritic...

Johri S.a*, Khan N.a and Shrivastava S.b

AMORPHOUS SOLID DISPERSIONS OF PIOGLITAZONE HYDROCHLORIDE USING CREMOPHOR RH 40 AND POLOXAMER 188: IN VITRO AND IN VIVO EVALUATION

PAGE 45-55

The study was aimed to improve dissolution and bioavailability of developed stable amorphous solid dispersions (SDs) of pioglitazone hydrochloride (PGH), a poorly water soluble drug. TGA showed compatibility with the polymers. The significant change in melting pattern of the PGH observed in the D...

Swain R. P.a,b* and Subudhi B. B.a

Assessment of Cancer Targeting Potential of Doxorubicin Conjugated with Surface Functionalized Multi-Walled Carbon Nanotubes

PAGE 56-70

Our main aim in the present investigation was to assess the cancer targeting potential of doxorubicin conjugated with folic acid (FA), ethylene di-amine (EDA) and surface F- MWCNTs (FA-EDA-MWCNTs- DOX) conjugate employing on MCF-7 (breast cancer cell line) for efficient tumor targeting. We develo...

Beldar V. K.a*, Uttekar P. S.a*, Patil A. R.a and Sable P. N.b

Dose dependent Antihyperlipidemic Activity of ethanolic extract of Mentha arvensis leaves in Triton and High Cholesterol Diet Induced rats

PAGE 71-80

A study was undertaken to evaluate antihyperlipidemic activity of ethanolic extract of leaves of Mentha arvensis in Triton and high cholesterol diet induced hyperlipidemic male albino Wstar rats. Acute hyperlipidemia was induced by administration of Triton WR-1339 (100 mg / kg i.v.) to t...

Ugare S.a*, Tarnalli A. D.b and khatib N. A.c

Short Notes

Insight into the structural requirements of sulfonyl derivatives based on Two and Three-dimensional descriptors: QSAR Studies

PAGE 81-86

The present work provides the rationale to the changes in the structure to have more potent analogs sulfonyl derivatives were reported to possess potent activity for the angiotensin AT1 receptor. We report here 2D QSAR and k-nearest neighbor molecular field analysis based mode...

Sharma M. C.a*

Novel Analytical Method development and validation for estimation of bromofenac sodium in bulk and pharmaceutical dosage form by Derivative and AUC spectroscopic method

PAGE 87-90

The present study was carried out to develop a simple and reliable derivative spectrophotometric method for the determination of bromofenac sodium in pharmaceutical dosage forms .The solutions of standard and the sample were prepared in distilled water The quantitative determination of the drug w...

Raghu. S.a, Muneer. S.a*, Chandra sekhar K.B.a and Siva Sai kiran B.a

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