Table of Contents

November  2019

  • Volume 56
  • Issue 11
  • Page Nos. 72

Guest Editorial

Strategies In The Current Intellectual Property Regime

PAGE 5-6

Dr. Gopakumar G. Nair is a Ph.D in Organic Chemistry (1966) from National Chemical Laboratory, Pune (Pune University). He was a Post-Doctoral fellow at IIT Bombay, Powai (1967) before joining the Pharma Industry. He was Director of Bombay Drug House P. Ltd., later Chairman of BDH Industries Ltd. ...

Dr. Gopakumar G. Nair
Editor,
Indian Drugs

Review Article

TOPICAL VITAMIN A DELIVERY: CHALLENGES, OVERVIEW OF NOVEL APPROACHES

PAGE 7-19

Vitamin A, commonly referred to as retinol, a fat soluble vitamin is an important nutrient involved in multiple functions within the human body which includes its role in the vision cycle, expression of genes,immunity, reproduction, epithelial cell growth and more. In the past years, dermal appli...

Manasiya M.a, Sawarkar S.a* and Bajaj A.a

Original Research Articles

DESIGN, MOLECULAR DOCKING OF SYNTHESIZED SCHIFF-BASED THIAZOLE/ PYRIDINE DERIVATIVES AS POTENT ANTIBACTERIAL INHIBITOR

PAGE 20-25

A series of N-(substituted benzylidene) thiazol-2-amines (3a-3d) and N-(substituted benzylidene) pyridyl-2-amines (3A-3D) were synthesized and individual structures were confirmed by several spectral techniques. Antibacterial activity of synthesized Schiff-base derivatives were performed by agar-...

Sahoo C. R.a,b, Patro R.b, Sahoo J.c, Padhy R. N.a and S. K. Paidesettyb*

ACUTE AND SUB-ACUTE TOXICITY STUDIES OF ETHANOLIC STEM AND ROOT EXTRACTS OF ARISTOLOCHIA RINGENS AND SECURIDACA LONGEPEDUNCULATA IN WISTAR RATS

PAGE 26-33

The aim of this study was to examine the acute and sub-acute toxicity of the ethanolic extract of the stem and root of Aristolochia ringens and Securidaca longepedunculata, respectively, in Wistar rats. The animals were divided into 5 per group and oral administration of extract at doses of 100, ...

Bankole A. E.a*, Adekunle A. A.a and Lawal A.a

METHOD DEVELOPMENT, VALIDATION AND PLASMA ANALYSIS OF ETORICOXIB USING LC-MS/MS IN INDIAN HEALTHY HUMAN VOLUNTEERS

PAGE 34-41

A rapid, highly sensitive, accurate and cost effective simple high performance liquid chromatographic tandem mass spectrometry (LC-MS/MS) method was developed and validated for the evaluation of cyclooxygenase-2 inhibitor etoricoxib in human plasma after administration of a single oral dose 60 mg...

Das S.a, Halder D.b, Dan S.a, Biswas E.b, Saha C.a and Pal T. K.b*

A VALIDATED HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHIC METHOD FOR LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE IN COMBINATION

PAGE 42-46

A high performance thin layer chromatographic method has been reported for estimation of losartan potassium with hydrochlorothiazide in combination. The analytes were resolved on precoated silica gel 60 F254 TLC plates prewashed with methanol using solvent system composition of chlorof...

Gawande V. V.a* and Chandewar A. V.a

AMELIORATION IN INSULIN RESISTANCE AND β-CELL FUNCTION BY DPP-4 INHIBITION POTENTIAL OF TRIGONELLA FOENUM SEED EXTRACT IN TYPE-2 DIABETIC RATS

PAGE 47-53

The current study was aimed to evaluate amelioration in insulin resistance, β-cell function and pancreas protection by DPP-4 inhibition potential of Trigonella foenum (TF) seed extract in corticosteroid induced type-2 diabetic rats by in slilico, in vitro and in vivo assays. The corticosteroid i...

Heera Rama, Anand Krishnaa, Kashyap P.b and Kumar S.b

EFFECT OF GLUCOCORTICOIDS EXPOSURE ON SERUM OSTEOCALCIN LEVELS

PAGE 54-58

Glucocorticoids (GCs) treatment has a profound effect on bone turnover and the mechanism is complex and not elucidated completely. One of the actions on bone explained by many studies is its effect on serum osteocalcin levels. To investigate changes in the osteocalcin levels among patients who ar...

Holla A.a, Vidyasagar S.a*, Nandakrishna B.a, Bairy L.b, Shastry B. A.a, Kamath A.c and Adiga S.d

Short Notes

MULTI-DOSE DRY POWDER INHALER: ADVANCE TECHNOLOGY FOR DRUG DELIVERY TO AIRWAYS

PAGE 59-62

Multi-dose dry powder inhaler (M-DPI) is a unique inhaler device from Teva Pharmaceutical developed for treatment of chronic respiratory diseases. It is a metered-dose dry powder inhaler system designed to appear as a typical pressurized metered-dose inhaler, but its internal geometry is very uni...

Mehta P.a*

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