Table of Contents

September  2019

  • Volume 56
  • Issue 09
  • Page Nos. 86

Guest Editorial

Need For Facilitating Innovation And Research

PAGE 5-6

Dr. Gopakumar G. Nair is a Ph.D in Organic Chemistry (1966) from National Chemical Laboratory, Pune (Pune University). He was a Post-Doctoral fellow at IIT Bombay, Powai (1967) before joining the Pharma Industry. He was Director of Bombay Drug House P. Ltd., later Chairman of BDH Industries Ltd. ...

Dr. Gopakumar G. Nair

Editor, Indian Drugs

Review Article

DRUG DELIVERY TO RETINA: A REVIEW

PAGE 7-21

The drug delivery to posterior segment especially to retina of eye is difficult due to various barriers. The diseases affecting the retina of eye are increasing and hence there is need to develop approaches for drug delivery to retina. This review describes the anatomy of retina, barriers associa...

Shelke D. A.a*, and Shirolkar S.a*

Original Research Articles

DESIGN, SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NOVEL BENZOTHIAZOLE BASED [1, 2, 4]-TRIAZOLO [4, 3-a] QUINOXALINE DERIVATIVES

PAGE 22-29

Quinoxaline, triazole and benzothiazole heterocycles plays an important role in modulating biological activity. The present work describes the biological evaluation of target molecules designed using autodock vina docker. Novel benzothiazole based [1, 2, 4]-triazolo [4, 3-a] quinoxalines were syn...

Gadhave R. V.a*, and Kuchekar B. S.a

A Comparative Study of In Vitro Antioxidant Potential, Photoprotective Screening of Ehretia acuminata R.Br. Leaves

PAGE 30-36

To evaluate the comparability of some of the most common radical scavenging assays using 2,2′-azinobis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS), 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, Ferric reducing power assay (FRAP) & nitric oxide. leaves of traditionally important medicinal ...

Shukla A.a* Kaur A.a*, Shukla R. K.b* and Anchalcc

STABLE LIQUID CHROMATOGRAPHY METHOD FOR THE RESOLUTION AND QUANTIFICATION OF RELATED IMPURITIES OF FOSAMPRENAVIR IN BULK AND PHARMACEUTICAL FORMULATIONS

PAGE 37-42

Highly resolved and validated Liquid Chromatography method was developed for the separation and quantification of fosamprenavir and its related impurity 2 and 5 in bulk and pharmaceutical formulations. Separation of fosamprenavir and its impurities was achieved on prontosil ODS C18 column using m...

Singh G. V. S.a*, Reddy D. R. S.b and Divakar T. E.c

DEVELOPMENT, VALIDATION OF RP-HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF TENOFOVIR DISPROXIL FUMARATE, EMTRICITABINE AND RILPIVIRINE HYDROCHLORIDE IN BULK, FORMULATION AND USED IN NANOSUSPENSION

PAGE 43-54

The present research work illustrates the development and validation of RP HPLC method for simultaneous estimation of tenofovir disproxil fumarate, emtricitabine and rilpivirine hydrochloride in bulk and formulated in a pharmaceutical dosage form as a nanosupension. Antiretroviral drug treatment ...

Vijaya Sri K.a*, Madhuri M.a, Anusha V.a and Siresha V.R.K.a

HPTLC Method Development and Validation for the Simultaneous Determination of Reserpine and Gallic acid in an Ayurvedic Formulation

PAGE 55-60

A simple, precise, accurate, robust HPTLC method was developed and validated for simultaneous estimation of reserpine and gallic acid in an Ayurvedic formulation. The two markers were resolved using TLC plates pre-coated with silica gel 60F254 using the mobile phase Toluene: Acetone: Glacial acet...

Adhyapak A.a*, and Jadhav A. P.*a

PHARMACOLOGICAL EVALUATION OF IN VITRO ANTI-OXIDANT AND IN VIVO ANTI-DEPRESSANT ACTIVITY OF ETHANOLIC BARK EXTRACTS OF ANNONA MURICATA ON MICE

PAGE 61-67

The aim of the present work was to evaluate the anti-oxidant and anti-depressant potentials of the Ethanolic bark extract of Annona muricata. Ethanolic bark extracts of Annona muricata was subjected to preliminary and quantitative phytochemical screening. In vitro Anti-oxidant activity of Annona ...

Ravishankar K.a, Sowmya P.V.S.C.P.aand Kiranmayi G.V.N.a*

Short Notes

RAPID HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR THE DETERMINATION OF RALTEGRAVIR IN HUMAN SALIVA

PAGE 68-73

In this study, a high-performance liquid chromatographic method (HPLC) was developed, validated and applied for the determination of raltegravir in biological sample like saliva. Liquid- liquid extraction was performed for isolation of the drug and elimination of saliva interferences. Samples of ...

Vijaya Sri K.a*, Shiva Kumar M.a Madhuri M. A.aand K. Sureshaa

STUDIES ON NANOLIPID EMULGEL OF NIMESULIDE FOR TRANSDERMAL DELIVERY

PAGE 74-77

The objective of the present study was to develop and evaluate a nanolipid transdermal emulgel of Nimesulide. The nanolipid particles of Nimesulide were developed using Compritol 888 ATO and Labrafil M1944 as lipids, Polysorbate 80 as surfactant with Poloxamer 188 and Polyethylene Glycol 400 as s...

Trimukhe C.a*, Patil P.a*, Sheth K.band Desai N.b*

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