Table of Contents

May  2020

  • Volume 57
  • Issue 5
  • Page Nos. 80

Guest Editorial

REPURPOSING OR SECONDARY USE OF KNOWN DRUGS

PAGE 5-6

Dr. Gopakumar G. Nair is a Ph.D in Organic Chemistry (1966) from National Chemical Laboratory, Pune (Pune University). He was a Post-Doctoral fellow at IIT Bombay, Powai (1967) before joining the Pharma Industry. He was Director of Bombay Drug House P. Ltd., later Chairman of BDH Industries Ltd. ...

Dr. Gopakumar G. Nair

Editor,

Indian Drugs

Review Article

BIODEGRADABLE NANOSPHERES - CURRENT STATUS

PAGE 7-18

Nanospheres are polymeric matrix of spherical shape that ranges in size between 10- 200 nm in diameter. The drug is dissolved, entrapped, encapsulated or attached to the matrix of polymer. The nature of nanospheres can be amorphous or crystalline, and they potentiate to protect the drug from chem...

Yarraguntla Srinivasa Rao a* and Kamala Kumari P. V.a

Original Research Articles

SYNTHESIS CHARACTERIZATION AND DOCKING STUDY OF HCV NS3/4A PROTEASE INHIBITOR MOLECULES

PAGE 19-31

A sharp rise in the number of hepatitis C patients has been observed worldwide in the last decades. This has attracted the attention of researchers and medical professionals to provide cheap and effective treatment options for the eradication of hepatitis C. The present study describes the synthe...

Kumar Satisha*, Santra P. K.b and Aryan R. C.b

PHARMACOGNOSTICAL AND PHYSICO-CHEMICAL SCREENING OF EUPHORBIA TIRUCALLI STEM-BARK

PAGE 32-42

Euphorbia tirucalli L. is a flowering shrub or tiny tree, indigenous to temperate regions. It is useful in the treatment of whooping cough, asthma, dyspepsia, colic, jaundice and some more ailments. Aim of the present investigation was to study pharmacognostical and physico-chemical screening of ...

Mali P. Y.a* and Goyal S.a

ASSESSMENT OF PHYTOCONSTITUENTS OF MEDICINAL IMPORTANCE FROM MILLETTIA PEGUENSIS ALI (SYN. MILLETTIA OVALIFOLIA KURZ)

PAGE 43-50

The present study was aimed to investigate the biologically active compounds present in the seed and leaf extracts of Millettia peguensis. Screening was done through preliminary qualitative analysis of phytochemicals and Gas Chromatography-Mass Spectroscopy (GC-MS) method. The study revealed the ...

Kaur Arshpreet*a and Sidhu M. C.a

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING ANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF CILNIDIPINE, CHLORTHALIDONE AND TELMISARTAN IN BULK AND TABLET DOSAGE FORM

PAGE 51-55

A simple, accurate and precise method was developed for the simultaneous estimation of cilnidipine, chlorthalidone and telmisartan in tablet dosage form on Agilent C18 column (150mmx4.6mm dia., 5µ particle size), using buffer and acetonitrile in the ratio of 55:45 V/V, which was pumped through t...

Goday Swapna *a , Shaik Abdul Rahaman,b and Avula Prameela Ranic

STABILITY INDICATING UPLC METHOD FOR ESTIMATION OF METFORMIN HYDROCHLORIDE AND NATEGLINIDE SIMULTANEOUSLY IN THE PRESENCE OF STRESS DEGRADATION PRODUCTS

PAGE 56-64

A novel Ultra Performance Liquid Chromatography (UPLC) method was developed and validated for the simultaneous determination of antidiabetic drugs metformin hydrochloride and nateglinide. The method was developed using a Waters ACQUITY UPLC SB C18 (100 × 2.1 mm, 1.8...

Prameela Rani A.a*, Madhavi S.a, Tirumaleswara Rao B.a and Sudheer Reddy CH.a

HEPATOPROTECTIVE ACTIVITY OF WHOLE FLOWER OF HIBISCUS ROSA-SINENSIS LINN EXTRACTS IN WISTAR RATS

PAGE 65-70

The aim of the present study was to evaluate the hepatoprotective effect of ethanolic and aqueous extracts of Hibiscus rosa-sinensis Linn flowers..Carbon tetrachloride-induced hepatic injury in rats and pentobarbitone induced hypnosis methods were used to evaluate the hepatoprotective activity. A...

Agrawal Krishna Kumar a*

Short Notes

SIMULTANEOUS DETERMINATION OF DOMPERIDONE AND SOME PRESERVATIVES IN ORAL FORMULATION: RP-HPLC METHOD

PAGE 71-73

A novel RP-HPLC method was developed and validated for the determination of compounds in an oral solution. The method describes the determination of domperidone along with sodium methylparaben, sodium propylparaben and sodium benzoate in liquid oral formulation. Chromatographic separations were p...

Patel Aasha.a, Firke Sandip D.b*, Patil Ravindra R.b, Kalaskar Mohan G.b, Bari Sanjay B.a and Surana Sanjay J.b

DETERMINATION OF BIOACTIVE CONTENTS AND IN VITRO ANTIOXIDANT ACTIVITY OF POLY HERBAL FORMULATIONS

PAGE 74-79

Free radicals are reactive molecules involved in many physiological processes and have been associated with many diseases, such as ageing, cancer, arthritis and liver injury and cardiac complications. In polyherbal formulations HAF-I and HAF-II, described below, the total phenolics content were f...

Srivastava A. Ka*, Kaushik D.b and Lal V. K.

Current Issue
September 2020
Quick Contact