Table of Contents

December  2023

  • Volume 60
  • Issue 12
  • Page Nos. 108

Print ISSN : 0019-462X

Guest Editorial

NANOBIOTECHNOLOGY: OPPORTUNITIES AND CHALLENGES

PAGE 5-6

Dear Reader,

Welcome to a comprehensive exploration of one of the most dynamic and promising frontiers of scientific inquiry and technological innovation: nanobiotechnology. The concepts of nanobiotechnology are relatively recent, originating from Richard Feynman’s idea of ‘There’s ...

Dr. Vandana B. Patravale

Institute of Chemical Technology, Mumbai

Review Article

CINNAMIC ACID AND ITS DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS

PAGE 7-19

Cinnamic acid is one of the naturally occurring chemical compounds present in various plants. It is obtained by both isolation from crude drugs, and by the synthetic route. In the last 10 years, many researchers have explored cinnamic acid for its pharmacological activities. Out of this anti-micr...

Snehal R. Thakara , Pooja N. Dhamadea and Deepali A. Bansodea *

Original Research Articles

EXPLORING THE BINDING MODES OF PIPERAZINE COMPOUNDS ON MAO-A FOR A STEP TOWARDS DEPRESSION THERAPY

PAGE 20-28

Sadness, often referred to as “depression,” is a normal emotion. The World Health Organization (WHO) claims that depression is a prevalent psychological condition that affects 264 million people worldwide, involving complex interactions between social and psychological behaviors. Piperazine, ...

Chahata , Keshav T. Jhaa , Abhimannu Shomea and Pooja A. Chawlaa *

MICROENCAPSULATION TECHNIQUE FOR SUNSCREEN GEL DEVELOPMENT: ENHANCING UV PROTECTION

PAGE 29-34

The current research looked at the sunscreen gel formulation using microbead technology via the ionotropic gelation method. Herbal oils such as jojoba oil and raspberry seed oil were used in our study due to their sun-protective qualities, which provide protection against both UV-A and UV-B rays....

Sabeel Salama *, Divya Va, Mohamad Hijasa and Nafiya Siraja

UNSATURATED FATTY ACID VESICULAR TOPICAL FORMULATION FOR THE TREATMENT OF SUPERFICIAL FUNGAL INFECTION

PAGE 35-42

Enhancement of skin bioavailability through topical formulation is challenging due to the presence of the barrier stratum corneum. Elastic, deformable lipid vesicles are easily penetrated through the skin barrier. The present study involves unsaturated fatty acid for vesicular preparation, ufosom...

Ashwini D. Patela *, Prachi Pandeya and Pooja V. Modia

SUSTAINED RELEASE FLOATING IN SITU GELLING SUSPENSION OF ACYCLOVIR

PAGE 43-53

Acyclovir has a 10-30 % oral bioavailability with a half-life of 2-3 h. Acyclovir mainly gets solubilized in acidic conditions, and its absorption is found in the upper GIT. The primary aim of this research work was to formulate gastroretentive dosage form of acyclovir that can float on gastric c...

Pallavi Chiprikara * and Nisharani Ranpisea

PHARMACOGNOSTIC EVALUATION OF APIUM GRAVEOLENS LINN. AND TRACHYSPERMUM ROXBURGHIANUM (DC.) CRAIB.: THE DRUG “AJMODA” IN INDIAN SYSTEM OF MEDICINE

PAGE 54-59

Two species, namely, Apium graveolens Linn. and Trachyspermum roxburghianum (DC.) Craib., are being popularly known as ‘Ajmoda’ in India and ‘Celery’ in English. Both the species belong to the family Apiaceae. The plant specimens are mostly collected from wild sources by unskilled collect...

Sagarika Paridaa *, Kedar K. Routb, Ananya Mishraa , Gyanranjan Mahalika and Nabin K. Dhalc

SPECTROPHOTOMETRIC ESTIMATION OF NERATINIB PHARMACEUTICALS: APPLICATIONS TO CHEMOMETRICS SUPPORTED ROBUSTNESS TESTING AND METHOD GREENNESS ASSESSMENT

PAGE 60-65

Neratinib is a novel anti-breast cancer agent approved for treating the early stages of breast cancer in women. Based on the non-availability of methods, the authors developed two UV spectrophotometric methods using water as a solvent. The drug shows a maximum absorption of 263 nm in water. Furth...

Sagar S. Pandaa * and Suman K. Mekapb

SIMULTANEOUS ESTIMATION OF three ANTIHYPERTENSIVE AGENTS BY ABSORBANCE CORRECTION METHOD

PAGE 66-74

The estimation of amlodipine besylate (AML), telmisartan (TEL) and chlorthalidone (CHL) in a tablet form has been carried out simultaneously using a straightforward, precise, accurate UV method using absorbance correction. This procedure involved the measuring of absorbance at three wavelengths u...

Sonal S. Zambrekara, Leena A. Sawaikara *, Surashree S. Gaudea, Pradnya G. Pala and Swati M. Kenya

EVALUATION OF ANTIUROLITHIATIC ACTIVITY OF FLEMINGIA STROBILIFERA R. BR IN ZINC DISC-INDUCED UROLITHIASIS: AN ANIMAL MODEL STUDY

PAGE 75-81

Kidney stones are painful and do not have complete successful therapy. Therefore, the objective of this work was to assess the antiurolithiatic activity of Flemingia strobilifera R. Br in zinc-induced nephrolithiasis. Preliminary phytochemical analysis of plant leaf extracts in chloroform was car...

Anil Kumara *, Anil Kumar K. V. a , Swaroopa Rani N. C.b, Aditya V. c and Girish B. S.c

Short Communications

INFLUENCE OF ALLIUM SATIVUM ON THE ANTIHYPERGLYCAEMIC ACTIVITY OF GLICLAZIDE IN DIABETIC RATS: AN HERB-DRUG INTERACTION STUDY

PAGE 82-84

In this particular study, the objective was to examine how varying doses of gliclazide (1 mg kg-1) and Allium sativum (104 mg kg-1) affect interaction in rats with diabetes induced by alloxan. The diabetes was induced by intraperitoneal injection of alloxan at a dosage of 100 mg kg-1 of body weig...

Aminabee Shaika *, Ch. Rammohan Raob and Lakshmana Rao Atmakuria

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