Table of Contents

November  2024

  • Volume 61
  • Issue 11
  • Page Nos. 84

Guest Editorial

CAN REGULATIONS BE “LESS PRESCRIPTIVE?”

PAGE 5-6

Dear Reader,

It is a fact that within a few years of the birth, the parents start introducing dos and don’ts for anything and everything. In today’s DINK/ DI1K (double income no kid/ double income one kid) lifestyles, the life of even that innocent young child gets regimented with lot...

Dr. D B Anantha Narayana,

PhD.

Editorial Advisory Board Member, Indian Drugs

Review Article

CELL SIGNALLING DYNAMICS IN THE HUMAN BODY PERTAINING TO CANCER

PAGE 7-19

Cell signalling is an intricate web of communication that plans and directs fundamental cellular functions. Normal tissue homeostasis, immunity, tissue repair and development - all depend on cells’ capacity to sense and react appropriately to their surroundings. Diseases including diabetes, can...

Phool Chandraa *, Zeeshan Alia , Nishat Fatmaa , Neetu Sachanb and Krishana K. Sharmaa

Original Research Articles

IN SILICO STUDY OF NSAIDs CONJUGATED WITH COUMARINS AS NEW ANTI-INFLAMMATORY COMPOUNDS

PAGE 20-29

The serious GIT side effects of NSAIDs, due to their carboxylic acid groups, aroused the attention of researchers to manipulate such drugs. Conjugates with NSAIDs are a strategic, way for both augmenting the anti-inflammatory activities and reducing side effects. Natural or synthetic coumarins ar...

Moath K. Bashira , Mahmood K. Oglaha * and Ahmed A. J. Mahmooda

DICLOFENAC SODIUM- CURCUMIN NANOGEL: AN EFFICIENT TOPICAL AGENT AGAINST INFLAMMATION

PAGE 30-39

The present study focuses on formulation of a topical nanogel of diclofenac sodium and curcumin to enhance the anti-inflammatory activity. Emulsification solvent evaporation technique was employed to prepare nanoparticles of the drugs. Various gel formulations containing optimized nanoparticles a...

Satyalakshmi Siragama *, Rama R. Boraa , Vineela Nakkaa , Srinivasa Rao Yarraguntlaa and Kamala Kumari P. V.a

FREE RADICALS AND ANTIOXIDANTS: COMPARATIVE IN VITRO STUDY OF CURCUMIN AND XANTHOGREEN™ PRODUCTS TO DEAL WITH OXIDATIVE STRESS

PAGE 40-49

Lifestyle disorders caused by imbalanced diet, stress, lack of sleep and exercise disturb the body’s homeostasis and cause oxidative stress. The generated reactive radicals damage different organ systems, causing hormonal imbalance, cardiac and respiratory disorders, and neurodegeneration. Our ...

Sanjivani A. Pathaka , Gayatri D. Sawaleb, Santosh C. Ghugeb and Sadhana Sathayeb*

ELUCIDATING THE ROLE OF AJMODA (APIUM GRAVEOLENS LINN) IN ISCHEMIC HEART DISEASE THROUGH NETWORK PHARMACOLOGY AND MOLECULAR DOCKING ANALYSIS

PAGE 50-57

A substantial amount of research suggests that ajmoda (Apium graveolens Linn) possesses anti-oxidant, anti-platelet, hypolipidemic, anti-inflammatory, antihypertensive and cardiotonic properties. These positive characteristics predispose this plant for use as a medicament for cardiovascular disea...

Jackulin J. Perairaa , Pooja Kumaria and Divya Kharea*

ASSESSMENT OF THE COMBINATION OF FENOFIBRATE AND SILDENAFIL IN ALZHEIMER’S DISEASE

PAGE 58-66

The purpose of the study was to evaluate the effectiveness of fenofibrate and sildenafil at various dosages in the treatment of Alzheimer’s disease. Sildenafil is an up-regulator of brain-derived neurotrophic factor (BDNF), whereas fenofibrate is a powerful PPAR-α activator. The typical medica...

Parnika M. Sosea and Gaurav M. Doshia *

Short Communications

SENSITIVE AND TRACE DETERMINATION OF ALBENDAZOLE BY SPECTROPHOTOMETRIC METHOD

PAGE 67-69

This study focuses on the interaction between albendazole and iron, forming a complex that exhibits unique properties. The albendazole-iron complex shows a maximum absorbance at 420 nm, indicating a strong interaction between the two components. This interaction results in a molar absorptivity, a...

Rashmi R. Panjavania , Sakshi V. Tripathia and Chandramauly R. Sharmaa *

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