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It is a fact that within a few years of the birth, the parents start introducing dos and don’ts for anything and everything. In today’s DINK/ DI1K (double income no kid/ double income one kid) lifestyles, the life of even that innocent young child gets regimented with lot...
Cell signalling is an intricate web of communication that plans and directs fundamental cellular functions. Normal tissue homeostasis, immunity, tissue repair and development - all depend on cells’ capacity to sense and react appropriately to their surroundings. Diseases including diabetes, can...
The serious GIT side effects of NSAIDs, due to their carboxylic acid groups, aroused the attention of researchers to manipulate such drugs. Conjugates with NSAIDs are a strategic, way for both augmenting the anti-inflammatory activities and reducing side effects. Natural or synthetic coumarins ar...
The present study focuses on formulation of a topical nanogel of diclofenac sodium and curcumin to enhance the anti-inflammatory activity. Emulsification solvent evaporation technique was employed to prepare nanoparticles of the drugs. Various gel formulations containing optimized nanoparticles a...
Lifestyle disorders caused by imbalanced diet, stress, lack of sleep and exercise disturb the body’s homeostasis and cause oxidative stress. The generated reactive radicals damage different organ systems, causing hormonal imbalance, cardiac and respiratory disorders, and neurodegeneration. Our ...
A substantial amount of research suggests that ajmoda (Apium graveolens Linn) possesses anti-oxidant, anti-platelet, hypolipidemic, anti-inflammatory, antihypertensive and cardiotonic properties. These positive characteristics predispose this plant for use as a medicament for cardiovascular disea...
The purpose of the study was to evaluate the effectiveness of fenofibrate and sildenafil at various dosages in the treatment of Alzheimer’s disease. Sildenafil is an up-regulator of brain-derived neurotrophic factor (BDNF), whereas fenofibrate is a powerful PPAR-α activator. The typical medica...
This study focuses on the interaction between albendazole and iron, forming a complex that exhibits unique properties. The albendazole-iron complex shows a maximum absorbance at 420 nm, indicating a strong interaction between the two components. This interaction results in a molar absorptivity, a...