Table of Contents

April  2024

  • Volume 61
  • Issue 4
  • Page Nos. 84

ISSN (Print) : 0019-462X

Editorial

SDGs, INNOVATION AND IP LICENSING

PAGE 5-6

Dear Reader,

United Nations have unanimously adopted the “Sustainable Development Goals” setting the 2030 Agenda for achievement, with the clarion call for action by all countries to set goals for meeting the targets by 2030. The SDGs are (1) Poverty (2) Zero Hunger (3) Good Health an...

Dr. Gopakumar G. Nair

Editor

Indian Drugs

Review Article

RECENT ADVANCES IN NANOTECHNOLOGY - BASED DRUG DELIVERY SYSTEMS FOR DELIVERY OF PHYTOCONSTITUENTS WITH SPECIAL EMPHASIS ON PSORIASIS MANAGEMENT

PAGE 7-15

Psoriasis is an inflammatory, autoimmune disorder characterized by thick and silvery lesions of the skin. Beyond its physical dimension, this disease has a significant adverse effect on quality of life and represents a huge social health burden. Based on symptoms, psoriasis may be characterized f...

Deepika Rania *, Vinit Kumar Sharmab, Bhupendra Chauhanb and Ranjit Singha

Original Research Articles

MOLECULAR DOCKING AND ADMET BASED MINING OF NATURAL COMPOUNDS FROM PTEROCARPUS MARSUPIUM AGAINST PRIME TARGETS OF DIABETES MELLITUS

PAGE 16-29

In the Ayurvedic system of medicine, Pterocarpus marsupium Linn bark extract is used for the treatment of diabetes. It has a rich profile of chemical constituents. However, phytochemicals with antidiabetic activity are not reported yet. To comprehend more about this plant’s antidiabetic mechani...

Siddhi S. Tambea *, Rohini R. Pujaria , Vishnu P. Chaudharia and Sandesh Lodhab

DESIGN AND OPTIMIZATION OF OCULAR INSERTS FOR PROLONGED DELIVERY OF CIPROFLOXACIN WITH CORTICOSTEROID

PAGE 30-37

Ocular drug delivery is very challenging and fascinating for pharmaceutical researchers, especially in the treatment of ocular conjunctivitis. The challenges include delivery of the drug to the eye without causing permanent tissue damage while maintaining a stable therapeutic level at the site of...

Swati M. Kenya *, Leena A. Sawaikarb and Anushka Savaikarc

DEVELOPMENT AND EVALUATION OF DOMPERIDONE ORAL FILM USING MIXED SOLVENCY CONCEPT

PAGE 38-45

This study aimed to develop and evaluate oral film of antiemetic drug-using mixed solvency concept. The mixed-solvency concept was used in the solubility enhancement of domperidone, an antiemetic drug that is practically insoluble in water. Different types of solubilizers have been used for solub...

Kirti Tomera *, Amit Kumar Jaina and Neha Gehlota

METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF IMATINIB MESYLATE SPIKED IN VITRO SALIVA BY LC-MS/MS

PAGE 46-56

A novel, sensible, rapid, reliable and economical analytical hyphenated LC-MS/MS method has been developed as a key for the safety surveillance in chronic leukemia patients, and as a part of therapeutic drug monitoring of imatinib mesylate in human saliva. Imatinib mesylate or imatinib methane su...

Swetha Sri Remidicherlaa,b, Guntupalli Chakravarthib*, Pravallika S.b, Alavala Rajasekhar Reddyb and GSN Koteswara Raob

PHARMACOLOGICAL EVALUATION OF COMMERCIALLY AVAILABLE POLYHERBAL FORMULATIONS FOR HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITIES

PAGE 57-64

Polyherbal formulations, are frequently used to treat liver dysfunction, preserve the liver, and regenerate the liver. This research was carried out to determine whether or not polyherbal formulations could protect the livers of mice exposed to carbon tetrachloride -induced hepatotoxicity. 13 gro...

Rajendra O. Ganjiwalea *, Pramod G. Yeoleb and Dilesh J. Singhavic

SAFETY ASSESSMENT OF AYURVEDIC GOLD MEDICATION SUVARNA BHASMA, IN WISTAR RATS

PAGE 65-71

Suvarna bhasma (SB) contains gold and lead, which are highly potent metals and are toxic in their crude form. This study evaluated the safety profile of the medication. Suvarna bhasma was administered for 90 consecutive days orally at three doses (10.23 mg kg-1, 40.92 mg kg-1 and 102.3 mg kg-1 bo...

Abhay N. Kulkarnia , Mahalaxmi Mohanb*, Pankaj S. Patilb, Mayuri D. Waghb, Shishir P. Pandec and Rajshree A. Kulkarnic

Short Communications

IN VITRO ANTIOBESITY ACTIVITY OF SOME PLANTS THROUGH A MODIFIED LIPASE INHIBITION ASSAY

PAGE 72-75

The objective of the present study was to evaluate the antiobesity potential of various plant (leaves or seed) extracts through a modified in vitro lipase inhibitory activity assay. Dimethyl sulphoxide (DMSO, negative control or solvent) extracts as cold infusion of leaves and seeds of some plant...

Radheshyama , Bhawna Basnala , Priyanka Gauniyaa, Mona Semaltya and Ajay Semaltya *

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