Article Details

Prevention of apparent adiposity by fractions of distilled cow urine: a non-invasive approach

Hatware Ketana*, Sharma Sanjaya, Deshpande Ashwinia, Patil Kirana, Karri Sravania and Gautam Rupeshb

a SVKM’S NMIMS, School of Pharmacy and Technology Management, Shirpur, Maharashtra - 425 405, India

b Department of Pharmacology, MM. School of Pharmacy, Maharishi Markandeshwar University Sadopur-Ambala 133 001, India

* For Correspondence E-Mail: ketanhatware02@gmail.com


ABSTRACT

Owing to the multifactorial pathological conditions management of obesity is a challenging problem. finding an effective and safe remedy is a huge area of interest for many scientists and healthcare professionals in the field of biomedicine. There is a traditional claim that fresh cow urine and its distillate have anti-obesity activity. The present study aimed to assess the bioactive fraction of distillated cow urine having anti-obesity potential. Distilled cow urine was extracted by liquid-liquid extraction method using different solvents. Distilled cow urine and all the fractions were assessed for the anti-obesity activity by analysing non-invasive parameters. The distilled cow urine and it’s methanolic as well as butanolic fractions show significant anti-obesity potential. It has been found that body weight reduced without affecting food consumption. This effect was probably due to the reduction in dietary fat absorption by reducing the pancreatic lipase activity and enhancing its excretion in faeces. Further research is required to explore the exact mechanism of action.

Year 2020 | Volume No. 57 | Issue No.3 | Page No. 73-78
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