Dear Reader,
This Guest Editorial could not have been better timed than now even though it should have given the call nearly ten years back! However, this editorial has become longer than what I envisaged, and seek your patience to read through it in your leisure time.
The positio...
Wound is a disruption of the normal anatomical structure and the tissue function. The wound healing or repair is an orderly process which involves multiple phases characterized by inflammation, proliferation and remodeling. Natural products, which are derived from herbs and animals, constitute se...
In the present research, newly developed complex with sodium caprylate was investigated for solubility and dissolution enhancement of eluxadoline. Complexes were prepared in different ratios by solvent evaporation method and characterised solubility study, Infrared spectroscopy (IR), Diffrential ...
A novel, simple, selective, rapid stability-indicating and LC-MS compatible short run time UPLC method was developed and validated for the determination of afatinib and its related substances in bulk and finished dosage form. A reverse phase gradient mode short run time method has been developed ...
2 Oxo-2h-chromene-3-carbohydrazide (1) reacts with various aromatic aldehydes to give corresponding 2-oxo-2h-chromene-3-carbohydrazide arylidene hydrazides (SB1-8). Oxidative cyclization of (SB1-8) with mercuric oxide and iodine in DMF medium furnishes the title compounds 3-(...
Gemcitabine hydrochloride niosomes were developed in our laboratory in an effort to improve the efficacy of the drug via development of nanotechnology based delivery system. As a part of this exercise, an analytical method was developed and validated to evaluate the developed formulation for assa...
Specific and innovative method was developed and validated for the identification and quantification of cefixime and erdosteine in the bulk and formulation samples by UPLC with PDA detector.The analytical technique was with buffer (pH: 7.0): methanol, (65:35%, v/v) us...
A simple Q-absorbance ratio method have been developed for the determination of dapagliflozin (DAPA) and saxagliptin (SAXA) in fixed dose combination (FDC) using UV-Visible spectrophotometer. In this method, the UV spectra of DAPA and SAXA were overlaid to obtain wavelength at isosbestic point (Î...
The Myristica fragrans (MF) is well known in Ayurveda for many therapeutic uses. The present research work was carried out to investigate the antioxidant (in vitro), sedative and hypnotic effects of the MFmilk extracts in Wistar rats. The extraction was carried out by hot percolatio...
The chemical constitution of Carica papaya leaves tablets and the fragmentation pattern of rutin is poorly investigated. Rutin was found to a constituent of tablet formulation. This work reports a study on the fragmentation pattern of rutin by electrospray ionization with multistage mass spectrom...
Emulgels (emulsion gels) are a class of biphasic semi-solid formulations, having aqueous and non-aqueous phases, delivering both hydrophilic and lipophilic agents. The main advantage of an emulgel is that lipophilic drugs can be easily formulated as emulgels. Rutin trihydrate is an herbal drug us...