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The pharmaceutical industry is undergoing a tremendous shift driven by the pursuit of increased therapeutic effectiveness, stability, and bioavailability of drugs. Among the many formulation options, cocrystal technology has emerged as a pioneering strategy. This editorial at...

Drug discovery and development an exclusively time and resources consuming technique. Computer aided drug discovery process minimizes the wet lab experiments and makes the process more economical. In this review, we outline the fundamental procedures involved in the drug discovery process and the...

Resorcinarene-based macrocycles have garnered significant attention in drug delivery due to their selfassembly properties and unique topology. This study focuses on synthesizing a new resorcinarenebased macrocycle, incorporating a nitrobenzene molecule and amine derivative, to enhance therapeutic...

Hydrochlorothiazide, a poorly soluble and also a poorly permeable drug of BCS class IV, was formulated into solid lipid nanoparticles (SLNs) using the microemulsion method. Precirol® ATO 5, Tween® 80 and Kolliphor® P 188 were employed as lipid, surfactant and co-surfactant, respectively. Optim...

Emblica officinalis Gaertn. is used in the Indian systems of medicine for the management of Type 2 diabetes mellitus (T2DM) because of its antioxidant effects. Nuclear factor erythroid 2-related factor 2 (NFE2L2) is an essential transcription factor for translating phase II antioxidant enzymes an...

The proposed study aimed to create and validate a technique for detecting impurities in drug substances, specifically targeting low levels of ethylenediamine in pharmaceutical raw materials. The method involved the use of benzoyl chloride as a derivatizing agent, during pre-column derivatization ...

Shilajitwadi vati, a traditional herbometallic formulation, is used for treating various ailments. This subchronic toxicity study evaluated its safety during extended oral administration due to the inclusion of heavy metals. In compliance with OECD guideline 408, animals were divided into four gr...

Thrombosis, the formation of blood clots in blood vessels, plays a key role in serious medical conditions such as cardiac arrest, deep vein thrombosis, lung embolism and ischemic stroke. Though, conventional thrombolytic agents like tissue plasminogen activators and streptokinase are effective, t...