Dear Reader,
Government of India is currently negotiating a limited trade deal with USA which is likely to be signed after the US elections. Although, the current negotiations do not cover the Intellectual Properties (IP) or Pharmaceuticals, a limited deal if concluded successfully is exp...
Psoriasis is a chronic inflammatory skin disease resulting in red silvery skin patches, increased dermal vascularity and keratinocyte hyper proliferation, particularly on extensor prominences and the scalp. There are some exogenous chemicals and endogenous sources which causes skin dysfunction du...
The prevalence of a novel coronavirus (2019-nCoV) in the last few months represents a serious threat as a world health emergency concern. Angiotensin-converting enzyme 2 (ACE2) is the host cellular receptor for the respiratory syndrome of coronavirus epidemic in 2019 (2019-nCoV). In this work, th...
The present work deals with the green synthesis of silver nanoparticle from aqueous extract of Pergularia daemia as reducing agent and evaluation of the antimicrobial potential of synthesized green nanoparticles (GNPs). The synthesized silver nanoparticles (SNPs) were characterized by Ultraviolet...
The present work was carried out with a view to analyze the major phytochemical compounds of Indian spices, dalchini (Cinnamon zeylanicum) bark and coriander (Coriander sativum) fruit. Hydro-alcoholic extracts were prepared from selected spices and analyzed for extract yield, loss on drying (LOD)...
Four different simple, accurate and precise UV-spectrophotometric methods have been developed for the estimation of palbociclib (PB) in bulk and in-house capsule dosage form by zero order (Method I), zero order AUC (Method II), ‘first order derivative UV-spectrophotometric (Method III), and fir...
A revers phase liquid chromatographic technique has been developed for the separation and determination of candesartan cilexetil and amlodipine besylate using QbD (Quality by Design) approach. The present method was optimised by introducing experimental design approach to identify the chromatogra...
Solid self-micro emulsification technique is the new approach for poorly water-soluble and poorly bioavailable drugs by allowing the drug substance to be incorporated into the oil phase and thus having the ability to permeate the GI membrane to a faster extent. Oleic acid, Tween 80, methanol and ...
The aim of the present research was to perform green synthesis of gold nanoparticles of isolated citrus bioflavonoid from Citrus sinensis (orange) peel extract and to evaluate its anticancer potential. Methanolic extract of orange peel was obtained by Soxhlet extraction and citrus bioflavonoid wa...
A novel simple, rapid, sensitive and stability-indicating RP-HPLC method was developed and validated for the determination of azelnidipine (ALDP) and its impurities 1 and 2. Resolution of drug, its potential impurities and degradation products were achieved by RP-HPLC on was performed on Prontosi...