Ageing is a natural process characterized by progressive deterioration of biological functions. Ageing causes both morphological as well as biochemical alterations in various body organs leading to deterioration of health. Proteins, enzymes and neurotransmitters are a...

The present work describes a simple, accurate and precise HPTLC method for simultaneous quantitation of ritonavir (RVR) and lopinavir (LVR) in tablet formulation. Chromatographic separation of both drugs was performed on precoated aluminum plates, silica gel 60 F254 a...

The poor bioavailability and therapeutic response exhibited by the conventional eye drops due to rapid corneal loss is overcome by the use of ion-activated gel forming systems that are instilled as drops;these undergo gelation in cul-de-sac mode. The present study des...

Acyclovir was formulated as oral controlled release matrix tablets using natural and synthetic polymers separately or in combinations. Tablets were prepared by direct compression method. The tablets were evaluated to thickness, weight variation test, drug content, har...

A series of biologically active benzimidazole derivatives (2a-2n) was synthesized by the reaction of o-phenylenediamine with the derivatives of benzoic acid in presence of 4N-HCl followed by the reaction with piperazine and formaldehyde to undergo Mannich reaction. Th...

Difference spectroscopic method is based on the principle that tolperisone hydrochloride can exhibit two different absorption spectra in basic and acidic medium. A stock solution (1 mg/ml) was prepared with distilled water. Further dilution was made by using 0.1 N sod...

The present study was an endeavor to evaluate anti-inflammatory and analgesic activity of methanolic extract of Ixora coccinea flowers (ICF-ME). The in vivo anti-inflammatory was evaluated in rats by using carageenan-induced paw edema, as an acute an...