Table of Contents

February  2014

  • Volume 51
  • Issue 02
  • Page Nos. 1-64

Review Article

BIOSIMILARS NEED OF THE FUTURE

PAGE 5-15
Biologics are the fastest growing segment of the pharmaceutical industry, offering innovative treatment for life threatening diseases. High costs make the treatment inaccessible to most patients. This, coupled with many biologics going off patent, have triggered interest in the affordable analogues ...
Sawarkar S.* and Kore A.

Original Research Articles

RP-HPLC METHOD DEVELOPMENT FOR THE ASSAY OF AMPHOTERICIN B

PAGE 16-20
A sensitive and precise HPLC procedure has been developed for the assay of amphotericin B in bulksamples and pharmaceutical formulations by using a C18 column [Kromosil, C18, (5 ?m, 4.6mm x 250mm; Make. Waters)], and mobile phase combination is 1% formic acid in water and acetonitrile in ratioof 45:...
Mohankrishna L.*, Reddy P. J., Reddy.B. P. and Navya P.

Evaluation of immunomodulatory activity of Hibiscus rosa sinensis (Jaswand) by ethanol-induced immunosuppression in rats

PAGE 21-28
The present study was planned to evaluate and compare the immunomodulatory activity of ethyl acetateextract (EAE 100 mg/kg p.o.) and standardized extract of H. rosa sinensis in terms of cyanidin chloride(SEC 4 and 8 mg/kg p.o.) from petals of H. rosa sinensis. Immunosuppression was induced by chroni...
Desai S. K.*, Mulgaonkar S.S. and Pandey C. H.

Investigation of Solubility Enhancement of Prasugrel Hydrochloride: Nanosuspensions and Cyclodextrin Inclusion Complexes

PAGE 29-38
The objective of this study was to investigate nanosuspensions, hydroxypropyl-?-cyclodextrin (HP?CD)complexes and SLS powders for enhancing the solubility and dissolution rate of Prasugrel HCl (PHCl)so as to reduce the fluctuations in its oral bioavailability. PHCl nanosuspensions were preparedusing...
Devara R. K., Reddipogu P., Kumar S., Rambabu B., Jithan A.* and Habibuddin M.

ISOLATION AND CHARACTERIZATION OF EXOPOLYSACCHARIDES FROM LACTIC ACID BACTERIA AND ITS USE IN FORMULATION DEVELOPMENT

PAGE 39-46
Exopolysaccharides (EPS) are polymers that consist principally of carbohydrates and are excreted bysome microorganisms onto the outside of their cell walls. Several strains of lactic acid bacteria (LAB) areable to produce EPS which can be used as natural additives to enhance the rheology and texture...
Gadad A. P.*, Singh R., Darbha N. S. and Dandagi P. M.

EVALUATION OF ANTIARTHRITIC ACTIVITY OF YOGRAJ GUGGUL FORMULATION IN FREUNDS ADJUVANT INDUCED POLY-ARTHRITIC RAT MODEL

PAGE 47-53
The paper discusses evaluation of antiarthritic activity of Yograj guggul formulation in freunds adjuvantinduced poly-arthritis rat model. The findings demonstrate that the treatment with Yograj guggulformulation (200, 400 mg/kg/day) for 14 days produced a significant anti-arthritic activity (decrea...
Kaneria M., Sharma G., Wadekar R. R., Pereira M. and Naik S. R.*

Short Notes

DEVELOPMENt OF ANTIULCER HERBOMINERAL FORMULATION ALCECARE

PAGE 54-59
A herbomineral formulation was developed in suspension form by using the herb, mineral and differentexcipient and named Alcecare. The formulation was prepared by mixing calculated quantity ofshatavari aqueous extract, fennel seed oil and praval bhasma to make smooth cream and then otherexcipients ad...
Prasad M., Rajput R.*, Kushwaha A. and Bharti R.
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