a Department of Pharmaceutical Chemistry, T. John College of Pharmacy, Bangalore- 560 083, Karnataka, India.
b Department of Pharmaceutical Chemistry, Raghavendra Institute of Pharmaceutical Education and Research, Anantapur- 515 721, Andhra Pradesh, India
c Jacobs Engineering Singapore PTE Ltd, 29 International Business park, #03-01, Acer building tower A, Singapore
* For Correspondence: vishak_dr@yahoo.co.in
https://doi.org/10.53879/id.57.09.11505
ABSTRACT
Novel [1,4]diazepino[2,3-g]quinoxaline derivatives 5a-5i were designed, synthesized and characterized by spectroscopic method and elemental analysis. The title compounds were screened for skeletal muscle relaxant. Among the synthesized analogs, compound 5g and compound 5h revealed significant skeletal muscle relaxant activity. The relationship between the functional group variation and the biological activity of the synthesized compounds is discussed.
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