ABSTRACT

The aim the study was to expand the area of tablet binders from gums and extracted polysaccharides to whole seed powders so as to reduce processing cost involved with other synthetic binders and involvement of whole seed benefits to single dosage form. In the present study, buckwheat seed powder was used in the concentrations of 1%, 2%, 4%, 6% and it was compared with binding capacity of 2.5% acacia in tablet formulation as direct compressible agent. Valsartan was used as a model drug. It was found out that 2% w/w concentration of buckwheat seed powder performed well and all the parameters were in good range.