Articles Accepted

A REVIEW ON NATURAL ANTI BIOFILM AGENTS FOR WOUND BIOFILM
by Dr. V Sankar, 10 May 2020

Biofilm may be a consortium of micro-organisms in which the cells of microbes attaches to every other on a living or non-living surfaces inside a self-produced matrix of extracellular polymeric substance. The bacterial or fungal colonies invade the surface of the wounds thereby delaying the healing cascade. The resistance is partially due to low metabolic rate of these colonies which directly impacts the action of oral or parenteral antibiotics. Hence there is an urgent need to develop antibacterial agent to regulate the biofilm growth and development. Last few decades have witnessed wide research studies attempting to investigate the anti-biofilm effects of natural products. This review will summarize the wound infections associated with biofilm, mechanisms of bacterial resistance due to biofilm and recent studies on discovery of natural products with their mechanism for inhibiting various bacterial biofilm that can be a promising candidate which could provide novel strategies for biofilm-associated infections.

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November 2020
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