Current Issue

November  2018

  • Volume 55
  • Issue 11
  • Page Nos. 90

Guest Editorial

CHALLENGES FOR GENERIC DRUG PRODUCERS

PAGE 5-6

In the fiercely competitive global market for generic drugs, the complexities and interconnectivities come to the fore when a drug is recalled. In recent months, as you may be aware, the sartans (also known as AT1 receptor antagonists, angiotensin II receptor blockers/antagonists) have come into ...

Dr. Nagaraj N. Rao
Associate Editor
Indian Drugs

Review Article

AMALGAMATION OF AYURVEDIC CONCEPT WITH MODERN MEDICAL PRACTICE TO MANAGE KIDNEY STONE DISEASE (UROLITHIASIS): AN ABBREVIATED REVIEW

PAGE 7-18

An age-old syndrome which possesses not only multifactorial etiological origins but also often associated with high rate of remission-rebound frequency during its management time is kidney stone (termed as urolithiasis). In Ayurveda, this syndrome is called as mutrakricchra and it is one...

Baghel D. S.a, Chopra S.b, Bhatia A.b and Tamilvanan S.a,c*

Original Research Articles

Synthesis, Cytotoxic Evaluation and Molecular Docking Studies of New 3-(1,3,4-Oxadiazolyl)-Quinolinone Derivatives Against Breast Cancer Cell lines

PAGE 19-31

A series of new substituted 3-(5-substituted-1,3,4-oxadiazol-2-yl)-4(1H)-quinolinone derivatives (5a-t) have been designed and synthesized using appropriate protocols. All of them were screened for cytotoxic activity against human breast cancer cell lines (MCF-7 and T47D...

Muthadi S.a, Guda R.b, Kasula M.b, Garlapati A.a, and Akkinepally R. R.c*

Design, synthesis, antibacterial and anticancer activity of 4-hydroxy-3-(2-substituted-2-thioxoethyl)-1-phenyl/ methylquinolin-2(1H)-one derivatives

PAGE 32-39

A series of title compounds, 4-hydroxy-3-(2-substituted-2-thioxoethyl)-1-phenyl/methylquinolin-2(1H)- ones were synthesized and purity of the compounds was ascertained by TLC. The structures of the synthesized compounds were characterized by IR, NMR (1HNMR and 13CNMR) and ma...

Karmali H. A.a, Mamle Desai S. N.a*, Shingade S. G.a, Palkar M. B.b and Biradar B. S.c

New aromatic alcohol, benzoyl glycosidic ester and anthraquinone derivative from the aerial parts of Phyllanthus fraternus Webster

PAGE 40-44

Phyllanthus fraternus Webster (Euphorbiaceae) is used in Indian traditional systems of medicine to treat diabetes, influenza, dyspepsia, indigestion, dysentery, jaundice, kidney stones, urinary tract diseases, vaginitis and skin eruptions. Phytochemical investigation of a methanolic extr...

Abuzer A.a,b, Jameel M.a,c and Ali M.a*

Potential of RP-HPLC-DAD-MS for the qualitative and quantitative analysis of dapagliflozin in tablets and degradants

PAGE 45-49

Dapagliflozin is a new drug of the gliflozin class which inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2). It is a recent drug in the market and the generic market may soon get flooded with it. Therefore, newer methods are required to control dapagliflozin in pharmaceuticals. I...

Agarwal B.a* and Gandhi S.b

DEVELOPMENT AND VALIDATION OF A UV SPECTROPHOTOMETRIC Q-ABSORBANCE RATIO METHOD FOR SIMULTANEOUS ESTIMATION OF EPERISONE HYDROCHLORIDE AND ACECLOFENAC IN BULK AND TABLET DOSAGE FORM

PAGE 50-56

A simple, sensitive, rapid, accurate, precise and economical Q-absorbance ratio method has been developed for the simultaneous estimation of eperisone hydrochloride and aceclofenac in combined dosage form. The solvent used was methanol:water (70:30 v/v). The iso-absorptive point was found to be 2...

Simoes M.a* and Almeida L.a

STABILITY INDICATING RP - HPLC METHOD DEVELOPMENT FOR THE SIMULTANEOUS ESTIMATION OF LAMIVUDINE, TENOFOVIR DISOPROXIL FUMARATE AND EFAVIRENZ IN BULK AND PHARMACEUTICAL FORMULATION

PAGE 57-63

A simple, accurate reverse phase high performance liquid chromatographic method has been developed for the simultaneous estimation of lamivudine, tenofovir disoproxil fumarate and efavirenz in bulk and pharmaceutical formulations. The analytical method development was carried on Agilent make HPLC...

Suryadevara V.a, Sasidhar R. L a*, Venkateswara Rao B.a, Ganesh Kumar T. N. V.a and Ratna Kumari P. K.a

WOUND HEALING ACTIVITY OF THE WHOLE PLANT OF MOMORDICA CHARANTIA LINN. IN RATS

PAGE 64-70

The aim of the present study was to explore the effect of wound healing activity of the whole plant of Momordica charantia Linn. in rats. The effect of aqueous ethanolic extract of Momordica charantia Linn. (Family; Cucurbetaceae) was evaluated on resutured incision, granuloma...

Singh M.P.a*, Sarangdevot Y.S.b and Sisodia S.S.c

Short Notes

DESIGN AND CHARACTERIZATION OF ALFUZOSIN HCL GASTRORETENTIVE FLOATING MATRIX TABLETS EMPLOYING HPMC K 100M

PAGE 71-73

The present investigation involves developing gastro retentive drug delivery systems (GFDDS) of alfuzosin HCl using HPMCK100M a is the matrixing agent and floating enhancer. Sodium bicarbonate in the acidic environment reacts with the acid and produces carbon dioxide. The gastro retentive tablets...

Vijaya Ratna J.a and Srinivasa R. B.a

TEMPERATURE AND pH RESPONSIVE POLYMERIC NANOPARTICLES FOR TARGETED OXALIPLATIN DELIVERY

PAGE 74-77

In the present study temperature and pH responsive co-polymer chitosan-g-poly(N-isopropylacrylamide) (CS-g-PNIPAAm) was synthesized, characterized and efficiently loaded with oxaliplatin. Nanoparticles were evaluated for their physicochemical properties. The drug loaded nanoparticles showed smoot...

Patil A. S.a* and Gadad A. P.a

Recent Issue
Quick Contact