India is a rich country in terms of biodiversity & natural products, but very little work is carried out on stereochemical & spectroscopic studies of natural products. Isomers of natural products are found to be active, but the detection of stereochemical/spectral data is not effectively ...

In the present study, a new series of picric acid derivatives including their Schiffs bases were synthesized and characterized by their physical (m.p., Rf value), analytical (CHN) and spectral (UV-Visible, IR,1 HNMR, MS) data. The synthesized compounds were screened for antimicrobial activity by ...

In the present study, the objective is to synthesize novel compounds from the benzimidazole moiety,recognized for its various biological potentials. Chalcone being a very good synthon was utilized to combine with the benzimidazole moiety to design agents with significant antimycobacterial activit...

The aim of present work was to develop a metformin hydrochloride sustained release tablet by aqueous coating. Eudragit RL and Eudragit RS were used for coating of tablets. Eudragit RL having 10% and Eudragit RS having 5% of functional quaternary ammonium groups, which give rise to pH independent ...

A simple, accurate, precise and specific simultaneous equation method has been developed and validated for simultaneous estimation of dextromethorphan hydrobromide and quinidine sulphate in their combined dosage form approved by USFDA (brand name Nuedexta capsules) in October 2010. Absorbances we...

A sensitive and efficient method was developed for the determination of carvedilol and its metabolite in human plasma by LC-MS/MS. Plasma samples were hydrolysed with beta-glucuronidase and the target compounds were extracted with liquid liquid extraction using diethyl ether in dichloro methane a...

Simple and practical method for isolation of marmelosin (also called as Imperatorin) from Aegle marmelos fruits has been developed. The powdered fruits were extracted with methanol and partitioned with petroleum ether and on further purification marmelosin was obtained. Identity of the c...