The aim of the present investigation was to design and characterize nanocrystal formulation of curcumin for diabetes therapy. Formulation was prepared by High Pressure Homogenization. HPH cycles and pressure range were screened by preliminary batches (T1 & T2). 15 cycles were optimized and th...

The objective of the present study was to develop a controlled release transdermal drug delivery systems of simvastatin using lipid vesicular systems incorporated in a Carbopol gel, which will control the release of drug, increasing the bioavailability of the drug and thus decreasing the dosing f...

A new RP-HPLC method for the quantitative determination of metformin and sitagliptin in human plasma was developed and validated as per US-FDA guidelines. The drug was spiked in the plasma and extracted with mobile phase by precipitation method. The extracted analyte was injected into Symmetry C1...

Two simple and sensitive visible spectrophotometric methods have been developed and subsequently validated for the estimation of lansoprazole in bulk and pharmaceutical formulation. Method A is based on formation of greenish blue colored complex with ferric nitrate and potassium ferricyanide whic...

A simple validated RP HPLC method for the estimation of rizatriptan benzoate in pharmaceutical dosage form and bulk was developed for routine analysis. This method was developed by selecting Agilent TC C18 (250 x 4.6 mm, 5 μ) column as stationary phase and acrylonibrile:water (45:55), pH adjuste...