Dear Reader,
It was way back in December 2014 that Ella Watson-Stryker was named TIMES Person of the Year for 2014 and featured on the Cover of Time Magazine. Dr Watson-Stryker was recognised with the honour, which she shared with all the healthcare workers who, under trying circumstances...
Artificial intelligence, a machine-learning process, builds a smart machine that simulates the performance of the human brain and possesses the capability of utilizing a massive amount of data required to achieve a specific goal through learning and problem solving. The idea of artificial intelli...
Thizolidine-2,4-dione (1), on reaction with p-fluorobenzaldehyde in the presence of piperidine and toluene, gives (Z)-5-(2-fluororobenzylidin)-thiazolidin-2,4-dione (2), which on reaction with indole and o-chlorobenzaldehyde in the presence of ethanol yielded final derivatives i...
The aim of the present study was to formulate fixed-dose combination tablets of metformin hydrochloride and teneligliptin hydrobromide hydrate. The extended-release core tablet consisted of a seal coating over metformin and outer layer coated by teneligliptin for immediate release using perforat...
The objective of the investigation presented here is to explore the pharmacognostical nature, phytochemical characterization and in vitro antioxidant activity of Cyphostemma setosum (Roxb.). Vitis setosa (Roxb.) synonymous to C. setosum (Roxb.), is a herbaceous...
A sensitive, selective, precise and accurate stability-indicating high-performance thin layer chromatographic method for analysis of budesonide (BUD) and formoterol fumarate dihydrate (FFD) was developed along with forced degradation study and validated according to ICH guidelines. Densitometry a...
A rapid high-performance liquid chromatographic method has been developed and validated for quantification of lamivudine and dolutegravir, used to manage HIV infections. Lamivudine and dolutegravir are separated as symmetrical peaks on the analytical column Inertsil ODS, 150 mm x 4.6 mm, 5.0 µm ...
Withania coagulans Dunal (fam. Solanaceae) is an indigenous plant used traditionally for the treatment of diabetes and associated complications. However, the mechanistic approach of antihyperglycemic potential of the plant is not scientifically validated. The present study was undertaken...
The objective of the present investigation was to enhance the solubility and dissolution rate of BCS class II drug nevirapine through scalable and commercially feasible solid dispersion approach by using Soluplus® (BASF) as hydrophilic carrier. The solid dispersion produced by melting...
A simple, specific, accurate, precise and stability indicating high performance liquid chromatographic method was developed and validated for the simultaneous estimation of empagliflozin and linagliptin using Thermo Scientific BDS C18 column (250 ×4.6 mm, 5 µm) with mobile phase cons...