Table of Contents

March  2026

  • Volume 63
  • Issue 3
  • Page Nos. 76

Editorial

REGULATORY AND INNOVATION HISTORY IN WEIGHT-LOSS GENERICS

PAGE 5-7

Dear Reader,

The year, 2026 and the month of March, 2026 is remarkably going down in history for multiple reasons and events. Oil and gas have taken the global news by storm with the war at Iran and gulf, while March 2026 has become most relevant for pharma industry, regulators and innova...

Dr. Gopakumar G. Nair

Editor

Indian Drugs

Review Article

PERSONALIZED CHRONOTHERAPY: BRIDGING PRECISION MEDICINE WITH CIRCADIAN THERAPEUTICS

PAGE 8-17

The integration of precision medicine with chronotherapy offers a cutting-edge approach to optimizing treatments by aligning them with both individual biological variability and circadian rhythms. Circadian rhythms, controlled by the suprachiasmatic nucleus (SCN), regulate key physiological proce...

Rajeswari Aletia *, Monika Nijhawanb, Mohammad Bakhatwarb, Srinivas Baratamc and Krishna Kishore Adireddyc

Original Research Articles

SYNTHESIS AND PHYSICOCHEMICAL CHARACTERIZATION OF IONIC LIQUID SYSTEMS OF POSACONAZOLE

PAGE 18-25

Aspergillosis, caused by Aspergillus niger, is difficult to manage due to the poor solubility of antifungal agents like posaconazole. To enhance its delivery, an ionic liquid (IL) of posaconazole was prepared in 1:4 and 1:5 molar ratios via employing solvent evaporation method. Structural charact...

Sofiya F. Mujawara *, Yogesh V. Porea , Deep M. Chaudharia , Vinayak V. Rasala , Siddhesh V. Rokadea and Lovely P. Jaina

MULTI-PATHWAY TARGETING IN ALZHEIMER’S DISEASE: MOLECULAR DOCKING ANALYSIS OF SIX MAJOR CONSTITUENTS OF VETIVERIA ZIZANIOIDES WITH KEY RECEPTORS

PAGE 26-37

Alzheimer’s disease (AD), a leading cause of dementia, is characterised by progressive cognitive decline and impairment in daily functioning. In this study, a molecular docking approach using AutoDock Vina was employed to evaluate the binding affinities of six major phytoconstituents from Vetiv...

Deepali M. Jagdalea , Swati R. Dhandeb , Gayatri C. Nadarb, Yashashree Sawanta , Kaustubh R. Battellua and Sampada S. Bhosaleb*

IN SITU GEL FORMULATION OF ESMOLOL HYDROCHLORIDE FOR OCULAR DELIVERY: A REPURPOSING STRATEGY

PAGE 38-43

This study investigates the repurposing of esmolol hydrochloride for ocular diseases such as cataract by formulating and evaluating a temperature-sensitive in situ gel for ocular delivery. The gel was prepared using thermosensitive polymers Poloxamer 407 (Kolliphor® P407), Poloxamer 188 (Kolliph...

Sunanda Premanand Patila,b, Gayatri Sawalea , Santosh Ghugea , Siddhesh Wadkarb, Tanisha Koreb, Shalvee Surveb, Aarti Yadavb and Sadhana Sathayea *

MOLECULAR MECHANISM OF ERANDA MOOLA (ROOT OF RICINUS COMMUNIS L.) IN THE TREATMENT OF OSTEOARTHRITIS WITH NETWORK PHARMACOLOGY APPROACH

PAGE 44-50

The development of single-drug therapy in Ayurveda has been ongoing. For osteoarthritis, Eranda is one such medication. Age, joint injury, obesity, and family history are some of the factors that contribute to osteoarthritis. A new medication that is safer and more effective is required for this ...

Anil Korallia*, Sri Venkata Krishnan Vb, Abisesh Muthusamyc and Kshama Mutalikd

SUSTAINABLE CHROMATOGRAPHIC METHODS FOR ESZOPICLONE: METHOD WHITENESS EVALUATION APPROACH

PAGE 51-59

Eszopiclone is employed in the treatment of insomnia. Various analytical techniques, including chromatography and ultraviolet-visible spectroscopy, have been reported in the literature for the determination of eszopiclone. A review of existing literature indicates variability in the reported degr...

Mrinalini C. Damlea * and Shruti S. Gaikwada

Short Communications

FORMULATION AND EVALUATION OF ANTIOXIDANT HERBAL HAIR MASK CONTAINING FLAXSEED AND RICE WATER FOR TOPICAL APPLICATION

PAGE 60-62

This study focuses an development and evaluation of an antioxidant-rich herbal hair mask incorporating flaxseed and rice water. This mask was formulated from natural ingredients possessing conditioning, moisturizing and reparative characteristics without the use of parabens and sulphates. It demo...

Deepika A. Jagadalea *, Mangesh R. Bhalekara , Janhavi M. Deokuteb, Sharvari M. Molkara and Ananya T. Chowdharya

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