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Drug repurposing, also known as drug repositioning or reprofiling, is a potentially transformative approach in drug discovery. Novel therapeutic applications for existing drugs, whether licensed, experimental, or previously discontinued drugs for disorders outside their origi...

Lignin a biopolymer originating from lignocellulosic biomass has drawn interest in pharmaceuticals and biomedicine because of its biocompatibility, low toxicity, biodegradability, antioxidant, UV-protective and antimicrobial characteristics. It acts as a sustainable substitute for synthetic mater...

The present study uses molecular dynamic simulations to investigate the molecular interactions, stability and pH responsive behavior of commercially available hypromellose phthalate enteric polymer in complex with drug diroximel fumarate under gastric pH 1.5 and intestinal pH 5.5, and physiologic...

Poor solubility of numerous pharmaceutical agents in aqueous medium, especially those that belong to Class II and Class IV of the BCS, is a major impediment to oral bioavailability. Natural polymers are under widespread development as carriers in solid dispersion systems due to their biodegradabi...

Trijatakadi gutika, a polyherbal formulation described in Siddasara Samhita in Mukharoga adhyaya in Kantaroga hara yogas, was chosen for investigation, and GC-MS analysis was performed to understand its constituent parts and its functions in Kantaroga. According to the results, Trijatakadi gutika...

The goal of the current study to develop and validate a stability indicating approach that would produce accurate data for valganciclovir HCl, whether for pharmacokinetics, acceptability, release, or stability studies. A UV-visible spectroscopic method that is accurate, precise, and economical is...

The in vitro antioxidant activity of the ethanolic extract of Coriandrum sativum (C. sativum) leaves was performed by DPPH scavenging and ferrous chelating methods. To induce allergic conjunctivitis, an intraperitoneal injection of 0.6 mL saline containing alum (2 mg), egg albumin (1 mg) and 1010...

A simple, precise and stability-indicating first-order derivative UV spectrophotometric method was developed for the estimation of maribavir in the presence of its acid hydrolysis degradation products. Maribavir is an antiviral agent used in the treatment of cytomegalovirus (CMV) infections, espe...