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“Phytopharmaceutical drug” includes a purified and standardised fraction with defined minimum four bio-active or phyto-chemical compounds (qualitatively and quantitatively assessed) of an extract of a medicinal plant or its part, for internal or external use of human bein...

Flavonoids are a class of natural polyphenolic compounds found in many plants such as vegetables, fruits, flowers and tea. Several biological, pharmaceutical and medicinal activities are already reported forthese natural products including anti-inflammatory, anti-carcinogenic, anti-mutagenic and ...

Quantitative structure-activity relationship (QSAR) studies were performed on a series of triazolone analogs to find the structural requirements activity by two-dimensional studies. The statistically significant best 2D QSAR model derived from partial least square analysis is correlated with some...

The current study reports the antioxidant activity of Ocimum basilicum. Central composite design (CCD) was used to study the effect of variables on the extraction using magnetic stirrer (MST). Three independent variables including temperature, extraction speed, and extraction time were s...

A comparative study was designed to evaluate the in vitro antidiabetic activity from the aqueous extract of dried pericarp of Prunus amygdalus Bail and ethanolic extract of dried flower of Hibiscus rosa-sinensis L. against the standard Acarbose.The aqueous extract of P....

The aim of the present study was to convert an Ayurvedic formulation, “trikatu churna”, into a polyherbal dispersible tablet. Standardization parameters were performed for raw materials, trikatu churna and its extract. The standardized extract was further used for formulation of the dispersib...

Flibanserin has been recently approved by the USFDA for treating female sexual interest disorder. It is currently not included in any of the Pharmacopoeias. No stability indicating method information about flibanserin has been reported in the literature. Flibanserin stock solution (1 mg/mL) was p...

A chemometric method, Partial Least Square, was applied for the simultaneous estimation of epigallocatechin gallate and curcumin in tablet formulation. Twenty five mixed sample solutions were prepared for chemometric calibration as training set and sixteen mixed solution for validation set using ...

In the recent years, the interests on the herbal medicines and their utilization for the treatment for various diseases have been increasing rapidly, even in those areas where modern medicine is available. Medicinal plants are the richest source of bioactive compounds used in the traditional and ...

The objective of this study was to evaluate the phytochemical and pharmacological screening of fruit extracts of Aegle marmelos using various in vitro methods. The antioxidant activity of the extracts was evaluated by using DPPH free radical scavenging and reducing power method, while well diffus...

The pigment melanin is directly responsible for imparting skin color and imbalance in its production may lead to hyper- or hypo-pigmentation. Hyperpigmentation is characterized by excessive deposition of melanin in the epidermal layer of the skin. In the growing field of bioactive cosmeceuticals,...