Dear Reader,
Pharmacy a unique profession in the dynamic world of healthcare, is pivoted at the intersection of science and technology which addresses the crucial needs of healthcare. Healthcare is continuously ridden with plentiful challenges, which could lead to serious consequences if ...
Multi-drug cocrystals (MDCs) have gained increasing interest in recent times. They are also known as drug-drug cocrystals. MDCs offer a promising approach in pharmaceutical development, where two or more active pharmaceutical ingredients (APIs) are cocrystallized with a neutral coformer to create...
Non-small cell lung cancer (NSCLC) primarily reveals overexpression of epidermal growth factor receptors (EGFR), driving uncontrolled and abnormal cell divisions in lung tissue. Gefitinib is a firstgeneration EGFR inhibitor that is widely used as first-line NSCLC treatment, hence PDB ID 4I22 was ...
Cimetidine is an orally administered anti-ulcer medication. This study aims to develop a gastro-retentive in situ gel containing the drug to enhance its oral bioavailability and provide prolonged release. The gel was prepared by incorporating an emulsion into a polymeric solution, resulting in a ...
Silymarin is a significant medication that is used to treat chronic liver disease and liver cirrhosis. The focus of the current study is on the development of UV based analytical procedures for silymarin quantification using quality by design methodologies. Materials and procedures selected signi...
The world is rife with parasitic diseases. There is a great need to develop methods to improve delivery of medicines. Solubility and chemical stability are crucial factors to be taken into account while creating medicines. Ionic liquids (ILs) are ion-based salts that melt at or are liquid at lowe...
The aim of the study was to determine the cardioprotective effect of daidzein in 5-fluorouracil-induced cardiotoxicity. The animals of the standard group were treated with carvedilol 10 mg kg-1, and DDZ5 and DDZ10 groups were treated with daidzein for 8 days at doses of 5 mg kg-1 and 10 mg kg-1, ...
For turmeric oil obtained from Curcuma longa L. and rosemary oil obtained from Rosmarinus officinalis L. there an limited reports for their effect against neurodegenerative disorders, besides the limited knowledge on formulation development and their evaluation for CNS disorders have tremendous f...