Table of Contents

May  2012

  • Volume 49
  • Issue 5
  • Page Nos. 1-70

Review Article

Scope and Need of Combination of Antihypertensive Drugs

PAGE 5-19

The recommendation for first-line therapy for hypertension remains a beta blocker or diuretic given in a low dosage. A target blood pressure of less than 140/90 mm Hg is achieved in about 50 percent of patients treated with monotherapy; two or more agents from different pharmacological classes ar...

Pattan S. R.*, Zanwar A. O., Wabale N. B. and Shetkar U. B.

Original Research Articles

Synthesis, Antimalarial Activity and Qsar Studies of Chalcones,N-Benzylidenesulfonamides and Chalconesulfonamides

PAGE 20-34

Malaria remains the major cause of human morbidity and mortality worldwide. Malaria, caused byPlasmodium species, is potentially life threatening, increasing in prevalence and becoming evenmore resistant to in-use drugs. In this article, synthesis of compounds from the series of chalcones,benzyli...

More A. H., Raul S. J. and Mahajan S. S.*

Phytochemical Investigation of Aerial Parts of Swertia tetragona Edgew

PAGE 35-38

Swertia tetragona Edgew (Gentianaceae) is a Himalayan herb used as a substitute for S. chirayita.Phytochemical investigation of its aerial parts yielded pregn-4-en-3?-ol, 1-methoxy-4, 5-dihydroxy-7-methyl xanthone and stigmasterol characterized on the basis of spectral data analysis.

...

Bhat Z. A., Ali M.*, Ansari S. H. and Naquvi K. J.

Compatibility Studies of Acetazolamide with Excipients by using HighPerformance Liquid Chromatography (Hplc) Technique

PAGE 39-46

Compatibility studies are essential for preformulation studies of formulation development. Acetazolamideis a carbonic anhydrase inhibitor used in the treatment and management of cardiac oedema, glaucomaand other conditions. The objective of this study was to evaluate the physical and chemical sta...

Murthy T. E. G. K.*, Bala Vishnu Priya M. and Suresh Babu V. V.

Enhancement of Follicular Delivery of Finasteride in Niosomaland Proniosomal Gel form for Treating Androgenetic Alopecia

PAGE 47-55

Finasteride has not been explored extensively for the treatment of androgenic alopecia. The present workwas aimed to enhance the follicular delivery of finasteride topically by niosomal and proniosomal carriersystems for treating androgenetic alopecia. Finasteride niosomes were prepared by thin f...

Vimal K. R.*, Sankar V., Srinivas C. R. and Kumaresan M.

Short Notes

Stability Study of Triphala Churna

PAGE 56-60

Triphala Churna is an Ayurvedic preparation, prepared by mechanical mixing of three fruit pericarppowders, Emblica officinalis Gaertn., Terminalia belerica Roxb. and Terminalia chebula Retz. It is soldin the market as over the counter drug and mainly used for constipation problems. The raw materi...

Desai A.* and Savardekar M.

Development and Validation of Rp-Hplc Method for the Estimation ofTrandolapril and Verapamil in Combined Tablet Dosage Form

PAGE 61-64

A reverse phase high performance liquid chromatographic method was developed and validated asper ICH guidelines for estimation of trandolapril and verapamil in combined tablet dosage form. Theseparation was obtained using a mobile phase consisting of acetonitrile and phosphate buffer adjustingpH ...

Rao A. L.* and Bhaskara R. V.

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