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Repurposing of drugs was most often a strategic approach, though by “serendipity” in few instances. Early practice of pharmacovigilance in USA, led to near ‘serendipitous’ addition to market value for many “first use” drugs. Glaxo-Welcome’s Bupropion brand “We...

Nanospheres are polymeric matrix of spherical shape that ranges in size between 10- 200 nm in diameter. The drug is dissolved, entrapped, encapsulated or attached to the matrix of polymer. The nature of nanospheres can be amorphous or crystalline, and they potentiate ...

A sharp rise in the number of hepatitis C patients has been observed worldwide in the last decades. This has attracted the attention of researchers and medical professionals to provide cheap and effective treatment options for the eradication of hepatitis C. The present study describes the synthe...

Euphorbia tirucalli L. is a flowering shrub or tiny tree, indigenous to temperate regions. It is useful in the treatment of whooping cough, asthma, dyspepsia, colic, jaundice and some more ailments. Aim of the present investigation was to study pharmacognostical and physico-chemical scre...

The present study was aimed to investigate the biologically active compounds present in the seed and leaf extracts of Millettia peguensis. Screening was done through preliminary qualitative analysis of phytochemicals and Gas Chromatography-Mass Spectroscopy (GC-MS) method. The study revealed the ...

A simple, accurate and precise method was developed for the simultaneous estimation of cilnidipine, chlorthalidone and telmisartan in tablet dosage form on Agilent C18 column (150mmx4.6mm dia., 5µ particle size), using buffer and acetonitrile in the ratio of 55:45 V/V, which was pumped through t...

A novel Ultra Performance Liquid Chromatography (UPLC) method was developed and validated for the simultaneous determination of antidiabetic drugs metformin hydrochloride and nateglinide. The method was developed using a Waters ACQUITY UPLC SB C18 (100 × 2.1 mm, 1.8...

The aim of the present study was to evaluate the hepatoprotective effect of ethanolic and aqueous extracts of Hibiscus rosa-sinensis Linn flowers..Carbon tetrachloride-induced hepatic injury in rats and pentobarbitone induced hypnosis methods were used to evaluate the hepatoprotective activity. A...