Anastrozole is a selective non-steroidal aromatase inhibitor and is the first drug approved by FDA in adjuvant hormonal therapy. Anastrozole was proved superior to tamoxifen for the treatment of hormoneresponsive breast cancer. In this review, we have highlighted the ...

The poorly water soluble drugs tend to have low bioavailability and this can be improved by several methods. Solid dispersion is a promising formulation approach to improve solubility and dissolution and ultimately oral bioavailability of these drugs. The aim of this ...

A simple, fast, accurate and precise reverse phase HPLC method is developed and described for the determination of ramelteon in tablet dosage form. Chromatography was carried on an ODS column using a mixture of acetonitrile and phosphate buffer pH 7.0 (35:65 V/V) as t...

Aqueous extracts of Ocimum sanctum Linn., Tinospora cordifolia (Willd.) Miers ex Hook. f. & Thoms, Withania somnifera Dunal, Avicennia officinalis Linn. and Rhizophora mucronata Lam. were included for the prese...

A new simple high performance thin layer chromatographic method for simultaneous determination of rupatidine fumarate and montelukast sodium in bulk and tablet dosage form was investigated. Chromatographic separation of the drugs was performed on aluminum plates preco...

The new mathematical model was developed by studying angle of slide using N, N-dimethyl acetamide, non-volatile liquid vehicle and prepared liquisolid tablets, in which the different concentrations of non-volatile liquid adsorbed over carrier and coating material sepa...

Zileuton is an orally active inhibitor of 5-lipoxygenase and found to inhibit leukotrienes (LTB₄ , LTC₄, LTD₄ , and LTE₄) formation and well-known for the effective treatment of asthma. Rapid, economical and simple ‘Zero o...