Tuberculosis (TB) is one of most prevailing diseases, responsible for the morbidity and mortality of a large number of populations worldwide. Traditionally, it has relied on a limited number of drugs such as isoniazid, rifampicin, ethambutol, streptomycin, ethionamide and pyrazinamide. However, m...

Thiadiazoles are synthesized by using aromatic acids and thiosemicarbazide. Schiff base reaction is followed and then thiadiazolotriazole derivatives are prepared by using hydrazine hydrate, isoniazid and unhydrous FeCl₃. All the synthesized compounds were characterized by IR, 1H-NMR a...

Brimonidine is an anti-glaucoma agent useful in treatment of intraocular pressure. In the present study an attempt was made to formulate ophthalmic inserts of brimonidine tartrate (BT) in combination with polymers like methylcellulose, carboxymethyl chitosan and HPMC. Prepared ocular films were e...

The proposed UV spectrophotometric method for estimation of acetazolamide is based on the official method for dissolution of acetazolamide tablets mentioned in the United States Pharmacopoeia XXXII. The monograph, however, does not provide basis for estimation of acetazolamide in the bulk drugs b...

This study was carried out to determine the effect of herbal medication on the clinical status of HIV infected persons especially on their CD4+ T lymphocyte count and viral load. The toxicity of the medication was also studied. 25 HIV positive individuals were taken for the study. They were treat...

A simple, precise, accurate, reproducible and robust analytical method was developed using reversed phase HPLC for quantitative estimation of lercanidipine in biological matrices. The method was validated as per the ICH and FDA guidelines. Analysis of the drug was per...

A RP-HPLC method was developed and validated for the determination of ramosetron hydrochloride in pharmaceutical formulation as per ICH and FDA guidelines. The method was carried out on a Phenomenex RP-C18 column using a mixture of methanol and water (95:5) in an isocratic mode. The flow rate is ...