Table of Contents

February  2013

  • Volume 50
  • Issue 2
  • Page Nos. 1-60

Review Article

Protease Inhibitors: A Review

HIV protease inhibitors were first invented between 1989 and 1994 by researchers working for thepharmaceutical companies of Hoffmann- La Roche Inc. (in Nutley, New Jersey), Abbott Laboratoriesand Merck & Co., Inc. HIV protease inhibitors are used in the treatment of patients with AIDS and wereconsid...
Sapkale P. V., Jadhav S. B. and Sable P. N.

Original Research Articles

Method Development and Validation of Olanzapine in Pure andPharmaceutical Dosage form by Rp-Hplc Method

A simple and reliable reverse phase high-performance liquid chromatography method was developed andvalidated for Olanzapine in pure and pharmaceutical dosage form. The method was developed on BDSHypersil C18, (150 mm x 4.6 mm, 3?m) with a mobile phase of 0.01M tetra butyl ammonium hydrogensulphate :...
Mastiholimath V.S., Dandagi P.M., Gadad A.P., Murali Krishna N.V.and Mannur V.

Quantitative Determination of Deferasirox in Bulk and PharmaceuticalFormulation by Uv Spectrophotometric Method

A simple, fast and reliable zero order spectrophotometric method was developed for determination ofdeferasirox in bulk and pharmaceutical dosage forms. Beers law was obeyed in concentration range of212 /ml deferasirox at 245.6 nm wavelength. The correlation coefficient was found to be (r2 = 0.999),p...
Marathe G. M., Pande V. V., Patil P. H., Mutha R. E. and Bari S. B.

Preclinical evaluation of nootropic activity of Glabridin Rich Extract ofGlycyrrhiza glabra using Passive Avoidance Paradigm in rats

The study was aimed at establishing the nootropic potential of Glycyrrhiza glabra using appropriateexperimental model. Nootropic activity evaluation of Glabridin Rich Extract (GRE) of roots and stems ofGlycyrrhiza glabra was carried out in rats using passive avoidance paradigm. In this model, scopol...
Desai S. K., Pandey C. H. and Mulgaonkar S.M.

Antihyperglycemic and In Vitro Antioxidant Activities of Punica Granatum Alloxan Induced Diabetic Rats

The present study was undertaken to evaluate antihyperglycemic and antioxidant activities of aqueousand methanolic extracts of leaves of Punica granatum. The aqueous and methanolic extracts (200 and400 mg/kg) of the leaves were tested for their efficacy in alloxan induced diabetic rats. Glibenclamid...
Patil U. S., Bandawane D. D., Bibave K. H. and Chaudhari P. D.

Short Notes

A Novel Method For Isolation of Mangiferin from Mangifera Indica L. Bark

A simple and practical method for the isolation of mangiferin from Mangifera indica Linn. (Anacardiaceae)(Mango) bark has been developed. The method involves solvent extraction of the dried bark powderusing a single solvent and further purification by recrystallization to yield pure mangiferin. Puri...
Gholkar M. S and Laddha K. S.

Anti-Inflammatory Effect of Seeds of Tamarindus Indica in Wistar Rats

Tamarindus indica L. is highly valued in Indian medicine for management of painful inflammation,diabetes and constipation. In the present study, the anti-inflammatory potential was evaluated usingcarrageenan induced rat paw edema model. The coarse seed powder was extracted with distilled water,ethyl...
Hivrale M. G., Mali A. A. and Bandawane D. D.
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