Table of Contents

February  2020

  • Volume 57
  • Issue 2
  • Page Nos. 76

Guest Editorial

Challenging Covid-19*

PAGE 5-6

Dr. Nagaraj Narayan Rao obtained Bachelor’s degrees in Science (Chemistry) and in the Technology of Pharmaceuticals and Fine Chemicals from the University of Mumbai. After working with Colgate-Palmolive (India) for two years as a laboratory chemist, he obtained his doctorate in science with mag...

Dr. Nagaraj N. Rao

Associate Editor

Indian Drugs

Review Article

A OVERVIEW ON ANTIMICROBIAL AND ANTI-INFLAMMATORY ACTIVITY OF 1, 3, 4-OXADIAZOLES

PAGE 9-17

1, 3, 4-oxadiazoles first came into the lime light about 80 years ago. With the increasing world population, the number of microbial infections has increased all over. To overcome the continuously spreading harmful microbial infections, the need for newer and newer drugs has increased tremendousl...

Singh Satvira,b*, Kaur Manpreeta, Bhandari Divyab, Kaur Mandeepa and Gupta Monikaa

Original Research Articles

Synthesis and anti-HIV Evaluation of substituted indole-3-carbaldehyde derivatives

PAGE 18-26

In the present study, a series of indole-3-carbaldehydes having substituted N-sulfonyl phenyl or Nphenacyl group was synthesized and evaluated for anti-HIV activity, in particular, in vitro and in silico HIV-1 integrase inhibition. Three compounds (8b, 8c and 8g) exhibited significant inhibition ...

Wadhwa Pankaja,b*, Jain Pritia,c and Hemant R Jadhava

PHYTOCHEMICAL ANALYSIS OF SEED OF MEDICINAL HERB, ARECA CATECHU LINN. AND EVALUATION OF IN-VITRO ANTHELMINTIC ACTIVITY OF ARECOLINE IN AQUEOUS AND ORGANIC EXTRACTs

PAGE 27-31

The objective of the study was to extract the active constituent of Areca catechu Linn (Arecaceae) and evaluate the anthelmintic effect of arecoline. liquid liquid extraction was used to extract the arecoline from areca nut. polar and nonpolar solvents were used for extraction. The anthelmintic a...

M. Sumithra*a, Ishwarya .N.a , Shanmugasundaram. P.a, Vijeyaanadhi. M.a and Dineshnath G.a

 

A HERBAL CREAM FOR ACNE VULGARIS

PAGE 32-40

The present work deals with the development and evaluation of a herbal anti-acne cream. Ethanolic fruit and leaf extracts of Myristica fragrans (Nutmeg) and Ficus religiosa (Pipal) were used for preparing the cream. Three creams namely, F1 (Myristica fragrans), F2 (Ficus religiosa) and F3 i.e. co...

Kashikar Vrushalia* and Tope Sonala

A NOVEL VALIDATED ANALYTICAL METHOD FOR THE ESTIMATION OF MIDODRINE HYDROCHLORIDE IN PHARMACEUTICAL FORMULATION BY LC-MS/MS

PAGE 41-44

A novel simple, precise, accurate and validated, liquid chromatography-tandem mass spectroscopy method has been developed for the quantitative determination of midodrine hydrochloride from a commercially available formulation. Caffeine was used as the internal standard. Isocratic separation was a...

Narenderan S.T., Meyyanathan S.N.*, Babu B. and Karthik Y.a

APPLICATION OF CHEMOMETRIC METHODS FOR DETERMINATION OF CLOTRIMAZOLE AND BECLOMETHASONE DIPROPIONATE IN PHARMACEUTICAL DOSAGE FORM

PAGE 45-50

Chemometry is the use of mathematical and statistical methods to improve the understanding of chemical information and to correlate quality parameters or physical properties to analytical instrument data. In the present work, two chemometric methods, named as principal component regression (PCR) ...

Shah Umang*a, Desai Bhumikaa and Nandrubarkar Vyomeshb

SIMULTANEOUS ESTIMATION OF DOXORUBICIN AND HYDROxyCHAVICOL IN BULK AND PHARMACEUTICAL FORMULATION BY Q-ABSORPTION RATIO METHOD

PAGE 51-58

A simple, rapid, accurate, precise and economical UV-spectrophotometric method has been developed and validated for simultaneous estimation of doxorubicin hydroxychavicol (DOXO) and OH-CHV in a pharmaceutical formulation. It is based on the Q-analysis UV Spectrophotometric method. The absorption ...

Bhusari Sachina*, Gotmare Bhartia and Wakte Pravina

Formulation and evaluation of Lipstick, Rouge and Eye shadow using colored pigment from the extract of Piper betel and Acacia catechu

PAGE 59-66

The present work was aimed to formulate various cosmetic formulations comprising of extract of Piper betel and Acacia catechu and limestone as a coloring agent to minimize the side effect(s) associated with the use of synthetic colorants. Different natural ingredients such as bees wax, carnauba w...

Randive D. S.a*, Bhinge S. D.b, Bhutkar M. A.a, Shejawal K. P.a., Mulla A. S.a, Thorat M. S.a and Patil P. D.a

Short Notes

DETECTION OF IMIDACLOPRID RESIDUES IN SPINACH BY HPLC AND ITS EFFECT ON ANTIOXIDANT ACTIVITY

PAGE 67-69

Imidacloprid is an insecticide for the control of green peach aphids on selected fruits and vegetables. Spinach (Spinacia oleracea) is used as a functional food for its wholesome nutritional, antioxidants and anti-cancer composition. In the present study, HPLC technique is applied to detect Imida...

Thorat Swapnali Ashoka, Dharanguttikar Vyankatesh Ravindraa, Adnaik Rahul Shivajia and Mohite Shrinivas Krishnaa

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING METHOD FOR IPRATROPIUM BROMIDE BY USING RP-HPLC

PAGE 70-72

A simple stability indicating RP-HPLC method was validated for determination of ipratropium bromide in the bulk drug. The drug was resolved using HPLC Column (Kromasil ODS 150 x 4.6 mm C18 column) with mobile phase of HPLC grade acetonitrile:potassium di-hydrogen phosphate buffer (60:40 V/V) at a...

Bansode Amola*, Patil Rohitb, Gaikwad Shubhangeeb and Shetti Pranavb

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