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Coronaviruses are a large family of zoonotic viruses, that is, the virus is transmitted from animals to humans. Although several common human coronaviruses are known, and usually lead upon infection to mild to moderate upper-respiratory tract illnesses, some coronaviruses cau...
1, 3, 4-oxadiazoles first came into the lime light about 80 years ago. With the increasing world population, the number of microbial infections has increased all over. To overcome the continuously spreading harmful microbial infections, the need for newer and newer drugs has increased tremendousl...
In the present study, a series of indole-3-carbaldehydes having substituted N-sulfonyl phenyl or Nphenacyl group was synthesized and evaluated for anti-HIV activity, in particular, in vitro and in silico HIV-1 integrase inhibition. Three compounds (8b, 8c and 8g) exhibited significant inhibition ...
The objective of the study was to extract the active constituent of Areca catechu Linn (Arecaceae) and evaluate the anthelmintic effect of arecoline. liquid liquid extraction was used to extract the arecoline from areca nut. polar and nonpolar solvents were used for extraction. The anthelmintic a...
The present work deals with the development and evaluation of a herbal anti-acne cream. Ethanolic fruit and leaf extracts of Myristica fragrans (Nutmeg) and Ficus religiosa (Pipal) were used for preparing the cream. Three creams namely, F1 (Myristica fragrans), F2 (Ficus religiosa) and F3 i.e. co...
A novel simple, precise, accurate and validated, liquid chromatography-tandem mass spectroscopy method has been developed for the quantitative determination of midodrine hydrochloride from a commercially available formulation. Caffeine was used as the internal standard. Isocratic separation was a...
Chemometry is the use of mathematical and statistical methods to improve the understanding of chemical information and to correlate quality parameters or physical properties to analytical instrument data. In the present work, two chemometric methods, named as principal component regression (PCR) ...
A simple, rapid, accurate, precise and economical UV-spectrophotometric method has been developed and validated for simultaneous estimation of doxorubicin hydroxychavicol (DOXO) and OH-CHV in a pharmaceutical formulation. It is based on the Q-analysis UV Spectrophotometric method. The absorption ...
The present work was aimed to formulate various cosmetic formulations comprising of extract of Piper betel and Acacia catechu and limestone as a coloring agent to minimize the side effect(s) associated with the use of synthetic colorants. Different natural ingredients such as bees wax, carnauba w...
Imidacloprid is an insecticide for the control of green peach aphids on selected fruits and vegetables. Spinach (Spinacia oleracea) is used as a functional food for its wholesome nutritional, antioxidants and anti-cancer composition. In the present study, HPLC technique is applied to detect Imida...
A simple stability indicating RP-HPLC method was validated for determination of ipratropium bromide in the bulk drug. The drug was resolved using HPLC Column (Kromasil ODS 150 x 4.6 mm C18 column) with mobile phase of HPLC grade acetonitrile:potassium di-hydrogen phosphate buffer (60:40 V/V) at a...