Table of Contents

April  2020

  • Volume 57
  • Issue 4
  • Page Nos. 72

Guest Editorial

Why Phytopharmaceutical Drug Discovery?

PAGE 5-6

S S Handa, a Pharmaceutical scientist/academician, Ph.D. from London School of Pharmacy, London (1972-75); Postdoctoral (1979-82) at the Department of Pharmacology & Pharmacognosy, University of Illinois at the Medical Centre, Chicago, USA; served as Professor and Head/Chairman of the Univers...

S S Handa

A Pharmaceutical scientist/academician

Original Research Articles

Molecular Docking and Design Study for Anticancer Activity of Flavonoid Derivatives Against Breast Cancer

PAGE 7-14

Flavonoids are a class of natural polyphenolic compounds found in many plants such as vegetables, fruits, flowers and tea. Several biological, pharmaceutical and medicinal activities are already reported forthese natural products including anti-inflammatory, anti-carcinogenic, anti-mutagenic and ...

Basma M. Abd Razika, Mohammed Oday Ezzatb* and Athmar Dhahir Habeeb Al-Shohanic

Structural requirements of some Triazolone derivatives using topological and physicochemical descriptors: QSAR approach

PAGE 15-19

Quantitative structure-activity relationship (QSAR) studies were performed on a series of triazolone analogs to find the structural requirements activity by two-dimensional studies. The statistically significant best 2D QSAR model derived from partial least square analysis is correlated with some...

Sharma Mukesh C.*a,b and Kohli D. V.b

EXTRACTION OPTIMIZATION OF THREE INDEPENDENT VARIABLES OF ANTIOXIDANTS FROM BASIL LEAVES USING RESPONSE SURFACE METHODOLOGY

PAGE 20-28

The current study reports the antioxidant activity of Ocimum basilicum. Central composite design (CCD) was used to study the effect of variables on the extraction using magnetic stirrer (MST). Three independent variables including temperature, extraction speed, and extraction time were studied th...

Alnasser Sulaiman M.a*

COMPARATIVE IN VITRO ANTIDIABETIC ACTIVITY OF PRUNUS AMYGDALUS (BAIL.) AND HIBISCUS ROSA-SINENSIS (LINN.)

PAGE 29-31

A comparative study was designed to evaluate the in vitro antidiabetic activity from the aqueous extract of dried pericarp of Prunus amygdalus Bail and ethanolic extract of dried flower of Hibiscus rosa-sinensis L. against the standard Acarbose.The aqueous extract of P. amygdalus and ethanolic ex...

Jyotia*

PREPARATION OF POLYHERBAL DISPERSIBLE TABLET AND EVALUATION BY RP-HPLC

PAGE 32-39

The aim of the present study was to convert an Ayurvedic formulation, “trikatu churna”, into a polyherbal dispersible tablet. Standardization parameters were performed for raw materials, trikatu churna and its extract. The standardized extract was further used for formulation of the dispersib...

Hegde Divyaa Hullatti Kirankumara* ,Parab Gaonkar Vishakhaa and Bolmal Uday Kumara

New Stability Indicating Method for Estimation of Purity of Flibanserin Active Pharmaceutical Ingredient

PAGE 40-44

Flibanserin has been recently approved by the USFDA for treating female sexual interest disorder. It is currently not included in any of the Pharmacopoeias. No stability indicating method information about flibanserin has been reported in the literature. Flibanserin stock solution (1 mg/mL) was p...

Chew Yik-Linga*, Lee Hon-Kenta and Bontha Venkata Subrahmanya Lokesha

DEVELOPMENT AND VALIDATION OF CHEMOMETRIC-ASSISTED UV-SPECTROPHOTOMETRIC METHOD FOR EPIGALLOCATECHIN GALLATE AND CURCUMIN IN TABLET FORMULATION

PAGE 45-51

A chemometric method, Partial Least Square, was applied for the simultaneous estimation of epigallocatechin gallate and curcumin in tablet formulation. Twenty five mixed sample solutions were prepared for chemometric calibration as training set and sixteen mixed solution for validation set using ...

Patel N. C.a*, Patel A. P.b, and Patel J. K.b

Formulation and evaluation of Herbal cough remedy from extract of Calendula officinalis L.

PAGE 52-58

In the recent years, the interests on the herbal medicines and their utilization for the treatment for various diseases have been increasing rapidly, even in those areas where modern medicine is available. Medicinal plants are the richest source of bioactive compounds used in the traditional and ...

Randive D. S.a, Bhinge S. D.b, Bhutkar M. A.a Joshi S. R. c, Patil P.D.c, Shejawal K. P.a,Thorat M. S.a and Mulla A.S. a

PHYTOCHEMICAL SCREENING AND PHARMACOLOGICAL EVALUATION OF AEGLE MARMELOS FRUIT

PAGE 59-64

The objective of this study was to evaluate the phytochemical and pharmacological screening of fruit extracts of Aegle marmelos using various in vitro methods. The antioxidant activity of the extracts was evaluated by using DPPH free radical scavenging and reducing power method, while well diffus...

Thaware Pratibhaa, KaralePushpa*b, Karale Maheshc and Chavan Pranatid

Short Notes

Evaluation of in vitro melanogenesis inhibition activity of Kadamba (Anthocephalus cadamba Miq.)

PAGE 65-66

The pigment melanin is directly responsible for imparting skin color and imbalance in its production may lead to hyper- or hypo-pigmentation. Hyperpigmentation is characterized by excessive deposition of melanin in the epidermal layer of the skin. In the growing field of bioactive cosmeceuticals,...

Kurve Siddhishaa, Khambete Mihirb* and Kadam Rupaa

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