Table of Contents

June  2020

  • Volume 57
  • Issue 6
  • Page Nos. 84

Guest Editorial

Pharmaceutical Education and research: Post the Covid-19 Pandemic

PAGE 5-6

Dr. George Patani is a Pharmacist from the College of Pharmaceutical Sciences, Manipal. He completed his Masters in Medicinal Chemistry and Ph.D. in Drug Delivery from Rutgers, The State University of New Jersey. He has approximately 20 years’ experience at the INGA group of companies, developi...

Dr. George Patani,

Associate Editor,

Indian Drugs

Review Article

MUCOADHESIVE BUCCAL DELIVERY OF DRUGS - CHALLENGES AND PRESENT ASPECTS

PAGE 7-20

Buccal delivery is an interesting route of delivery owing to the easy administration of drugs. Buccal delivery releases the drug into the oral cavity and promotes absorption through the oral mucosa and transmucosa to achieve local and systemic actions. This route of delivery can be successfully u...

H. V. Raghavendra Reddy And Bhattacharyya Sayani*

Original Research Articles

BIOLOGICAL SYNTHESIS OF SILVER NANOPARTICLES USING VICIA FABA EXTRACT AND ASSESSING ITS ANTIBACTERIAL ACTIVITY

PAGE 21-25

The biological method  provides a simple and efficient route for the synthesis of silver nanoparticles (AgNPs). The present study was aimed to synthesize AgNPs using Viciafaba seed extract as a reducing agent, which is a cost-effective, safe and eco-friendly method. The advantage of selecting th...

Chowdary Pavania*, Vishnu Pa, Patlolla Tejaswini Reddya, Bhaskara Rajeswareea,  Karre Akshara Gouda And Malyala Rachanaa

DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF NAPHAZOLINE HCL AND PHENYLEPHRINE HCL IN EYE DROPS

PAGE 26-31

A first order derivative UV-spectrophotometric method was developed to quantify naphazoline hydrochloride and phenylephrine hydrochloride in eye drops. Naphazoline hydrochloride and phenylephrine hydrochloride were estimated at 275.6nm (zero crossover point of phenylephrine hydrochloride) and 289...

Patel Satish. A.a And Baria Dharmendrasinh. A.b*

SENSITIVE BIO ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF VENETOCLAX IN HUMAN PLASMA BY LC-ESI-MS/MS

PAGE 32-38

A specific and sensitive method of liquid chromatography–tandem mass spectrometry was demonstrated for the experimental determination of venetoclax in human plasma utilising venetoclax-D8 as an internal standard. The column Xbridge C18, 50 × 4.6mm, 5 µm was used for attaining chromatographic ...

Potluri H.a*

FORMULATION DESIGN AND OPTIMIZATION OF FAST DISINTEGRATING TABLETS OF VALSARTAN: EFFECT OF SUPERDISINTEGRANTS

PAGE 39-48

Oral disintegrating tablets are a novel attractive dosage form in which the tablet disintegrates or dissolves in the buccal cavity within seconds without the use of water. The major drawback in designing this dosage form is unpleasant taste and low solubility of active entity. Valsartan is an ant...

Kamboj Sweta*a, Kamboj Rohita And Kumar Guarvea

IN-SILICO AND IN VITRO ASSESSMENT OF SYNTHESIZED DIAZENYLSULFONAMIDES AS APOPTOSIS INDUCERS AND RADICAL SCAVENGERS

PAGE 49-59

A series of eight quinoline-thiazole hybrid-bearing diazenylsulfonamides, 4a-4h, were synthesized and characterized by UV-Vis, FT/IR, 1H NMR and lC-MS. These compounds were formed when two prepared intermediate precursors of Schiff-base compounds, (E)-N-((2-chloroquinolin-3-yl)methylene)-4phenylt...

Sarangi Priyambada Kshiroda Nandinia*, Sahoo Jyotirmayab, Sahoo Chita Ranjanc,  Paidesetty Sudhir Kumarc And Mohanta Guru Prasadd

EFFECT OF OLMESARTAN ON PHARMACODYNAMICS AND PHARMACOKINETICS OF GLIMEPIRIDE AND METFORMIN COMBINATION IN ANIMAL MODELS

PAGE 60-68

To establish the safety and efficacy of drug-drug combinations in diabetic hypertensive patients, the present study was designed to identify the pharmacodynamic and pharmacokinetic influence of olmesartan on glimepiride + metformin combination in normal rats, diabetic rats and normal rabbits usin...

Beere Nagarajua* And Anil Kumar Kva

Short Notes

DESIGN AND EVALUATION OF CHITOSAN-HPMC POLYMERIC FILMS FOR TRANSDERMAL DELIVERY OF CAPTOPRIL

PAGE 69-72

Drug permeation through the skin layers remains a major challenge in transdermal drug delivery. In this study, the permeation enhancing property of chitosan together with its rate-controlling property has been utilized in the development of an efficient transdermal delivery system, using captopri...

Rajesh Sreedharan Naira*, Balamurugan Manickamc and Teng Meng Shengb

NATEGLINIDE SILICA LIPIDHYBRID PARTICLES FOR IMPROVED SOLUBILITY

PAGE 73-78

Porous silica-based drug delivery systems have shown substantial potential for improving the oral delivery of poorly water-soluble drugs.The major problem with nateglinide, a BCS Class II drug, is pHdependent solubility, limited aqueous solubility, poor dissolution and variable bioavailability. T...

Tiwari Shradhaa, Wadher Shaileshb and Gattani Surendrac

Current Issue
September 2020
Quick Contact