Dear Reader,

A wave of new innovative ideas utilizing the power of aggregation and information technologies, resulted in large disruptions across various industries with the creation of large virtual companies like Uber, Ola, Airbnb, Oyo etc. These companies,which were less capital intens...

Buccal delivery is an interesting route of delivery owing to the easy administration of drugs. Buccal delivery releases the drug into the oral cavity and promotes absorption through the oral mucosa and transmucosa to achieve local and systemic actions. This route of delivery can be successfully u...

The biological method  provides a simple and efficient route for the synthesis of silver nanoparticles (AgNPs). The present study was aimed to synthesize AgNPs using Viciafaba seed extract as a reducing agent, which is a cost-effective, safe and eco-friendly method. The advantage of selecting th...

A first order derivative UV-spectrophotometric method was developed to quantify naphazoline hydrochloride and phenylephrine hydrochloride in eye drops. Naphazoline hydrochloride and phenylephrine hydrochloride were estimated at 275.6nm (zero crossover point of phenylephrine hydrochloride) and 289...

A specific and sensitive method of liquid chromatography–tandem mass spectrometry was demonstrated for the experimental determination of venetoclax in human plasma utilising venetoclax-D8 as an internal standard. The column Xbridge C18, 50 × 4.6mm, 5 µm was used for attaining chromatographic ...

Oral disintegrating tablets are a novel attractive dosage form in which the tablet disintegrates or dissolves in the buccal cavity within seconds without the use of water. The major drawback in designing this dosage form is unpleasant taste and low solubility of active entity. Valsartan is an ant...

A series of eight quinoline-thiazole hybrid-bearing diazenylsulfonamides, 4a-4h, were synthesized and characterized by UV-Vis, FT/IR, 1H NMR and lC-MS. These compounds were formed when two prepared intermediate precursors of Schiff-base compounds, (E)-N-((2-chloroquinolin-3-yl)methylene)-4phenylt...

To establish the safety and efficacy of drug-drug combinations in diabetic hypertensive patients, the present study was designed to identify the pharmacodynamic and pharmacokinetic influence of olmesartan on glimepiride + metformin combination in normal rats, diabetic rats and normal rabbits usin...

Drug permeation through the skin layers remains a major challenge in transdermal drug delivery. In this study, the permeation enhancing property of chitosan together with its rate-controlling property has been utilized in the development of an efficient transdermal delivery system, using captopri...

Porous silica-based drug delivery systems have shown substantial potential for improving the oral delivery of poorly water-soluble drugs.The major problem with nateglinide, a BCS Class II drug, is pHdependent solubility, limited aqueous solubility, poor dissolution and variable bioavailability. T...