a School of Pharmacy, Devi Ahilya University, Takshashila Campus, Indore, Madhya Pradesh - 452 001, India
b Department of Pharmaceutical Sciences, Dr. H.S. Gour University, Sagar, Madhya Pradesh - 470 003, India
* For Correspondence E-mail : sharmamcdr2013@rediffmail.com
https://doi.org/10.53879/id.57.04.11853
ABSTRACT
Quantitative structure-activity relationship (QSAR) studies were performed on a series of triazolone analogs to find the structural requirements activity by two-dimensional studies. The statistically significant best 2D QSAR model derived from partial least square analysis is correlated with some of the parameters, viz. correlation coefficient (r2)with external ability of predictive activity. The results of this study may be useful to medicinal chemists to design more antihypertensive compounds.
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