Article Details

FORMULATION, DEVELOPMENT AND EVALUATION OF TOPICAL INTRADERMAL DRUG DELIVERY SYSTEM FOR ANTI-ACNE PRODUCT

Kashish Wilsona , Anjali Saharanb, Pooja Mittalc , Rupesh K. Gautamd* and Vipin Sainie

a Department of Pharmaceutics, MM College of Pharmacy, Maharashi Markandeshwar (Deemed To Be University), Mullana-Ambala-133 207, Haryana, India

b Department of Pharmaceutics, MM School of Pharmacy, Maharashi Markandeshwar University, Sadopur-Ambala-134 007, Haryana, India

c Department of Pharmaceutics, School of Pharmaceutical Sciences, RIMT University, Mandi Gobindgarh- 147 301, Punjab, India

d Department of Pharmacology, MM School of Pharmacy, Maharashi Markandeshwar University, Sadopur-Ambala-134 007, Haryana, India

e Maharashi Markandeshwar University, Kumarhatti-Solan- 173 212, Himachal Pradesh, India

For Correspondence: E-mail: drrupeshgautam@gmail.com

 

https://doi.org/10.53879/id.58.05.12693


ABSTRACT

The objective of the present study was to explore the anti-acne activity of herbal drug extracts of curcumin by making complexes with varying concentrations of soya lecithin using the phase inversion technique. The preformulation studies were performed and indicated that using the resultant formulation FIM4 shows the maximum potency outcomes. The characterization and evaluation were carried using Fourier Transform Infrared Spectroscopy (FTIR) and using various parameters such as appearance, texture, pH determination, viscosity, spreadability, stability, drug content, saponification value, irritation, antibacterial activity and in vitro diffusion. From the study, it was concluded that the optimized formulation FIM4 show the best resulting potency with antimicrobial properties.

Year 2021 | Volume No. 58 | Issue No.5 | Page No. 46-51
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