ABSTRACT

In this present study, a series of pyrazole terminated imino naphthyl derivatives were synthesized by the condensation reaction between 1,3 - diphenyl pyrazol-4-carboxaldehyde with substituted aromatic amines. The compounds were analyzed for their in vitro antimicrobial activities against some bacterial and fungal species and compared with the standard drugs. The molecular docking studies with protein and DNA were also carried out and revealed that all the synthesized compounds showed moderate to good biological activities, both experimentally and theoretically.