ABSTRACT

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Drug repurposing, also known as drug repositioning or reprofiling, is a potentially transformative approach in drug discovery. Novel therapeutic applications for existing drugs, whether licensed, experimental, or previously discontinued drugs for disorders outside their original indications, are explored in a drug repurposing approach. Repurposed candidates bypass early-stage development, usually progressing directly to advanced preclinical or clinical phases, reducing both cost and duration. In 2024, it was forecasted that the drug repurposing market size would increase by USD 8.58 billion at a CAGR of 4.3% between 2023 and 2028.