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Analgesic and Anti-Inflammatory Activities of Ixora Coccinea Flower

Aher A.N., Pal S. C. and Muke S. A..


ABSTRACT

The present study was an endeavor to evaluate anti-inflammatory and analgesic activity of methanolicextract of Ixora coccinea flowers (ICF-ME). The in vivo anti-inflammatory was evaluated in rats by usingcarageenan-induced paw edema, as an acute anti-inflammatory model. Quantitative estimation of totalpolyphenolic content of I. coccinea flowers was estimated by ICF-ME (100mg/kg) significantly decreasedpaw volume, after oral administration of ICF-ME in carrageenan injection. ICF-ME also exhibit significantanalgesic activity. The response of licking or jumping latency was recorded in seconds by using hotplate method. Presence of phytochemical like flavonoids, glycosides, and tannins in the ICF-ME mightcontribute to the observed analgesic and anti-inflammatory activity.
Year 2013 | Volume No. 50 | Issue No.1 | Page No. 64
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