Article Details

Evaluation of antioxidant potential of Caralluma attenuata

Sama V.*, Rajesh B., Krishnaiah A., Ravikiran A., Reddy B. M. and Mullangi R.

G. Pulla Reddy College of Pharmacy Mehdipatnam, Hyderabad- 500 028, Andhra Pradesh, India.

 

*E-mail: venkateshsama@hotmail.com

 

https://doi.org/10.53879/id.50.04.p0026


ABSTRACT

Antioxidant activity of ethanolic extract of Caralluma attenuata was evaluated for its free radical scavenging property in different in vitro models. The extract showed good dose dependent free radical scavenging property in all models except in inhibition of nitric oxide radical and lipid peroxidation. IC50 values are found to be 10, 14, 110 µg/mL in DPPH, super oxide and hydroxyl radical scavenging assays, respectively. Measurement of total phenolic compounds by Folin Ciocalteau phenol reagent indicated that 1 g of extract contain 450 mg of GAE/g. The results indicate that the antioxidant property of extract may be due to high content of phenolic compounds.

Year 2013 | Volume No. 50 | Issue No.4 | Page No. 26-33
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